• Students Looking at lab equipment in Cancer Research Center Students Looking at lab equipment in Cancer Research Center

    Biomedical Sciences

About

The Department of Biomedical Sciences trains students to be outstanding research scientists for careers in research, teaching and/or public health in academia, government, or the private sector. The department is the result of a partnership between the Wadsworth Center, part of the New York State Department of Health, and the University at Albany. Research addresses the biological aspects of public health problems, including antibiotic resistance, disease vectors, and tumor metastasis. The academic programs offers a unique ability to interact with both research and clinical labs to address urgent public health concerns related to the categories shown below. You’ll work with experienced mentors and researchers to gain fundamental insights into the biological processes that give rise to disease.

Our Department offers three graduate programs: The Master of Public Health (MPH), the Masters of Science in Biomedical Sciences, and the PhD in Biomedical Sciences. MPH students can perform research in a laboratory for internship credit, providing an immersive research experience. The MS and PhD degrees in biomedical sciences are even more research-intensive, and the PhD program offers extensive training for independent research projects. MS students have the option to perform their research project in the clinical laboratories located at the Wadsworth Center.

 

Biomedical Sciences Virtual Information Sessions

Please check back soon for upcoming virtual information sessions!

 

Portrait of Keith Derbyshire
Keith Derbyshire
News Feature: Keith Derbyshire

Learn more about Biomedical Sciences Professor Keith Derbyshire, who was named a fellow of both the American Association for the Advancement of Science and the American Academy of Microbiology. The awards recognize his scientific contributions to the fields of bacterial conjugation and transposition.  

Department of Biomedical Sciences
Anthony Torres
Administrative Manager

1 University Place
Rensselaer, NY 12144
United States

Office Hours

Virtual: Monday - Friday, 8 am-4:30 pm

Faculty

Distinguished Professor, Senior Advisor of RNA Institute
Clinical Associate Professor
Research Associate Professor
Clinical Assistant Professor
Assistant Professor
Associate Professor
Clinical Assistant Professor
Associate Professor
Associate Professor
Associate Professor
Clinical Assistant Professor
Assistant Professor
Empire Innovation Professor
Clinical Associate Professor

Programs

Masters

Biomedical Sciences MS | STEM |

Public Health MPH | +JD Option |

Public Health MPH | +JD Option |
Public Health MPH | +JD Option |
Public Health MPH | +JD Option |
Public Health MPH | +JD Option |
Public Health MPH | +JD Option |
Public Health MPH | +JD Option |
Doctoral

Biomedical Sciences PhD | STEM |

Biomedical Sciences PhD | STEM |

Research

Research Themes
Cancer and Stem Cells

Faculty in cancer and stem cells conduct research aimed at understanding the genetic and environmental causes of cancer. Research is focused on the underlying biology associated with tumor initiation and progression, and on the development and evaluation of chemopreventive regimens and therapeutic approaches for common cancers. Current lines of investigation include the study of noncoding RNAs in breast and prostate cancer, identifying key regulators of human placenta development, molecular alterations of the metabolism of cancer cells, breast cancer stem cells, and animal modeling approaches to tumorigenesis.

Faculty in this area:

  • Doug Conklin
  • Jason Herschkowitz
  • BK Lee
  • Sally Temple
  • JoEllen Welsh
Clinical

Faculty within the clinical theme characterize and test for clinically relevant pathogens. They develop modern sequence-based detection methods as well as traditional serological assays. These laboratories focus on pathogen surveillance and sequencing new variants from human and environmental samples. Current viral research includes detecting HIV-2 RNA and correlating genetic changes with pathogenesis in SARS-CoV-2 strains.  Additional projects involve identifying drug-resistance mechanisms in Candida and characterizing novel bacterial pathogens. Clinical faculty provide training to graduate students and Wadsworth fellows.  All graduate students may rotate in clinical laboratories. Only MS students may complete their thesis in a clinical lab. MPH students may do a clinical internship.

Faculty in this area:

  • Sudha Chaturvedi
  • Denise Kay
  • William Lee
  • Kirsten St. George
  • Klemen Strle
  • Linda Styer
Drug Discovery and Therapeutics

The goal of this research concentration is to discover and develop therapeutic molecules that will target known pathogens, neutralizing them from the body. A successful pursuit of drug discovery requires a deep understanding of the pathogen’s method of functioning, so that new therapeutics can be specific, effective, and safe for the patient. Our researchers are employing a variety of methods to identify new targets and the molecules that selectively inhibit them. Structural analysis methods such as cryo-EM, NMR, and X-ray crystallography are used to understand the mechanism of pathogen transmission and replication, to uncover unique molecular targets for inhibition. Methods such as high-throughput small molecule screening, antibody studies and animal models are utilized to identify potential therapeutics against these targets. These therapeutics can then be further modified for effectiveness and specificity with the help of genetic and bioinformatic analysis, and site-directed mutagenesis. Our faculty are using these approaches and more to counteract some of the most urgent threats to public health today, including Covid-19, tuberculosis, Lyme disease, and virulent bacterial infections.

Faculty in this area:

  • Raj Agrawal
  • Yi-Pin Lin
  • Nick Mantis
  • Jon Paczkowski
  • Janice Pata
  • Klemen Strle
  • Haixin Sui
Infection and Immunity

Faculty in the infection and immunity theme study the biological mechanisms of infectious agents and the host immune response.  Various disciplines, from molecular biology and genomics to entomology, are employed to investigate infectious diseases.  Research topics include antibiotic resistance strategies in Mycobacteria and Staphylococcus, transcription regulation in Salmonella and quorum sensing in Pseudomonas.  Additional research topics are the immune response in Lyme progression, antibody development against bacterial toxins, and insect-pathogen interactions in Anopheles and Ixodes species.

Faculty in this area:

  • Alex Ciota
  • Jan Conn
  • Keith Derbyshire
  • Pallavi Ghosh
  • Todd Gray
  • Yi-Pin Lin
  • Nick Mantis
  • Kathleen McDonough
  • Anil Ajha
  • Jon Paczkowski
  • Klemen Strle
  • Haixin Sui
  • Joe Wade
Structural Biology

Faculty in the structural biology theme study the effect of macromolecular shape on cellular function.  Protein and nucleic acid structures are combined with biochemical analyses, to understand the binding and catalytic mechanisms used.  Research topics include quorum sensing receptor-ligand interactions and DNA polymerase kinetics in bacteria, as well as mitochondrial ribosome function and ciliary microtubule structure in eukaryotes.

Faculty in this area:

  • Raj Agrawal
  • Nick Mantis
  • Kathleen McDonough
  • Anil Ojha
  • Jon Paczkowski
  • Janice Pata
  • Haixin Sui
Genes and Genomes

Faculty in genes and genomes theme are focused on the function, regulation, and evolution of genes in vitro, in vivo, and in silico. Researchers use a range of model systems, both prokaryotic and eukaryotic, as way of understanding the flow and use of information within genetic networks. The BMS department places an emphasis on understanding the underlying basis of disease, with a strong focus on infectious disease and cancer. Researchers use a wide range of techniques from whole genome sequencing, transcriptomics, proteomics, and bioinformatics. To this end, researchers in the BMS department have gained insight on how infectious Mycobacteria are capable of survival in the host, the mechanisms underlying antibiotic resistance, the mechanisms of bacterial cell-cell communication that control biofilm formation, the function of CRISPR for bacteria immune response, and the function of genes essential to cancer progression.

Faculty in this area:

  • Keith Derbyshire
  • Doug Conklin
  • Pallavi Ghosh
  • Todd Gray
  • Jason Herschkowitz
  • BK Lee
  • Anil Ojha
  • Jon Paczkowski
  • Janice Pata
  • Klemen Strle
  • Joe Wade
Research Publications
2020

Onygenalean Fungi as Major Human and Animal Pathogens

Journal: Mycopathologia

Author(s): Chaturvedi, Vishnu

 

Long noncoding RNA BHLHE40‐AS1 promotes early breast cancer progression through modulating IL‐6/STAT3 signaling

Journal: Journal of Cellular Biochemistry

Author(s): Chittur, Sridar; Herschkowitz, Jason

 

Increased temperatures reduce the vectorial capacity of Aedes mosquitoes for Zika virus

Journal: Emerging Microbes & Infections

Author(s): Ciota, Alexander

 

Mycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistance

Journal: Proceedings of the National Academy of Sciences of the United States of America

Author(s): Ghosh, Pallavi

 

Evidence for family-level variation of phenotypic traits in response to temperature of Brazilian Nyssorhynchus darlingi

Journal: Parasites and Vectors

Author(s): Conn, Jan

 

Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes

Journal: Trends in Parasitology

Author(s): Madison- Antenucci, Susan

 

Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin

Journal: NPJ Vaccines

Author(s): Mantis, Nicholas

 

Analysis of small non-coding RNAs in urinary exosomes to classify prostate cancer into low-grade (GG1) and higher-grade (GG2-5)

Journal: Journal of Clinical Oncology

Author(s): Tenniswood, Martin

 

Characterization of Primed Adaptation in the Escherichia coli type I-E CRISPR-Cas System

Journal: bioRxiv

Author(s): Wade, Joseph

 

Widespread divergent transcription from prokaryotic promoters

Journal: bioRxiv

Author(s): Wade, Joseph

 

A fluorescent plasmonic biochip assay for multiplex screening of diagnostic serum antibody targets in human Lyme disease

Journal: PLOS ONE

Author(s): Lasek-Nesselquist, Erica; Lin, Yi-Pin

 

Epidemiology of Cryptosporidiosis, New York City, New York, USA, 1995-2018

Journal: Emerging Infectious Disease

Author(s): Madison-Antenucci, Susan

 

The Factor H-binding site of CspZ as a protective target against multi-strain, tick-transmitted Lyme disease

Journal: Microbial Immunity and Vaccines

Author(s): Mantis, Nicholas

 

Effects of external low intensity focused ultrasound on electrophysiological changes in vivo in a rodent model of common peroneal nerve injury

Journal: Neuroscience

Author(s): Shin, Damian

 

Expression of Small Non-coding RNAs in Urinary Exosomes Classifies Prostate Cancer into Indolent and Aggressive Disease

Journal: The Journal of Urology

Author(s): Tenniswood, Martin

 

A methodological investigation of a flexible surface MRI coil to obtain functional signals from the human olfactory bulb

Journal: Journal of Neuroscience Methods

Author(s): Iannilli, Emilia

 

Brucella abortus RB51 Infections Associated with Consumption of Raw Milk from Pennsylvania-2017 and 2018

Journal: MMWR Morbidity and Mortality Weekly Report

Author(s): Egan, Christina

 

Laboratory Analysis of an Outbreak of Candida auris in New York from 2016 to 2018: Impact and Lessons Learned

Journal: Journal of Clinical Microbiology

Author(s): Haley, Valerie; Chaturvedi, Vishnu; Blog, Debra; Lutterloh, Emily; Chaturvedi, Sudha

 

IFCC Working Group Recommendations for Correction of Bias Caused by Noncommutability of a Certified Reference Material Used in the Calibration Hierarchy of an End-User Measurement Procedure

Journal: Clinical Chemistry

Author(s): Rej, Robert

 

Inclusive Science: Inspiring 8th Graders from Underrepresented Groups to Embrace STEM with Microbiology and Immunology

Journal: Journal of Microbiology and Biology Education

Author(s): DeJesus, Magdia

 

Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide

Journal: Stem Cell Reports

Author(s): Boles, Nathan; Temple, Sally

 

Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell Line

Journal: Viruses-Basel

Author(s): Ciota, Alexander

 

Detecting Cryptosporidium in Stool Samples Submitted to a Reference Laboratory

Journal: The American Journal of Tropical Medicine and Hygiene

Author(s): Madison- Antenucci, Susan

 

Baloxavir for the treatment of Influenza in allogeneic hematopoietic stem cell transplant recipients previously treated with oseltamivir

Journal: Transplant Infectious Disease

Author(s): St. George, Kirsten

 

The Factor H-Binding Site of CspZ as a Protective Target against Multistrain, Tick-Transmitted Lyme Disease

Journal: Infection and Immunity

Author(s): Mantis, Nicholas

 

Kin28 depletion increases association of TFIID subunits Taf1 and Taf4 with promoters in Saccharomyces cerevisiae

Journal: Nucleic Acids Research

Author(s): Knoll, Elizabeth; Morse, Randall

 

Frequency and magnitude of seroreactivity to Babesia microti in 245 patients diagnosed by PCR in New York State

Journal: Diagnostic Microbiology and Infectious Disease

Author(s): Madison-Antenucci, Susan

 

Isolation of a novel intertypic recombinant human mastadenovirus B2 from two unrelated bone marrow transplant recipients

Journal: New Microbes and New Infections

Author(s): St. George, Kirsten

 

Use of Functional Magnetic Resonance Imaging to Assess How Motor Phenotypes of Parkinson's Disease Respond to Deep Brain Stimulation

Journal: Neuromodulation

Author(s): Shin, Damian

 

In Vitro Evaluation of Toxicant Influences on the Immune System

Journal: Current Protocols in Toxicology

Author(s): Lawrence, David

 

H-reflex conditioning during locomotion in people with spinal cord injury

Journal: Journal of Physiology-London

Author(s): Thompson, Aiko; Wolpaw, Johnathan

 

Transcriptional profiling of Vibrio cholerae O1 following exposure to human anti- lipopolysaccharide monoclonal antibodies

Journal: Pathogens and Disease

Author(s): Baranova, Danielle; Levinson, Kara; Wade, Joseph; Mantis, Nicholas

 

Evaluating the Effects of Cell Sorting on Gene Expression

Journal: Journal of Biomolecular Techniques

Author(s): Chittur, Sridar

 

New twists on long noncoding RNAs: from mobile elements to motile cancer cells

Journal: RNA Biology

Author(s): Herschkowitz, Jason

 

Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models

Journal: Cells

Author(s): Temple, Sally

 

Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model

Journal: Journal of Immunology

Author(s): Chen, Xiang Yang; Chittur, Sridar

 

Conditional DnaB Protein Splicing Is Reversibly Inhibited by Zinc in Mycobacteria

Journal: Molecular Biology and Physiology

Author(s): Belfort, Marlene

 

Brain Iron Accumulation and the Formation of Calcifications After Developmental Zika Virus Infection

Journal: Journal of Neuropathology and Experimental Neurology

Author(s): Snyder-Keller, Abigail; Bolivar, Valerie; Kramer, Laura

 

Redefining fundamental concepts of transcription initiation in bacteria

Journal: Nature Reviews Genetics

Author(s): Wade, Joseph

 

Polycysteine-encoding leaderless short ORFs function as cysteine-responsive attenuators of operonic gene expression in mycobacteria

Journal: Molecular Microbiology

Author(s): Lasek-Nesselquist, Erica; Wade, Joseph; Derbyshire, Keith; Gray, Todd

 

Outbreak of botulism type A in dairy cows detected by MALDI-TOF mass spectrometry

Journal: Journal of Veterinary Diagnostic Investigation

Author(s): Egan, Christina

 

Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation

Journal: Nature Communications

Author(s): Agrawal, Rajendra; Banavali, Nilesh

 

Multiplexed non-invasive tumor imaging of glucose metabolism and receptor-ligand engagement using dark quencher FRET acceptor

Journal: Theranostics

Author(s): Mazurkiewicz, Joseph

 

Nanopore MinION Sequencing Reveals Possible Transfer ofbla(KPC-2)Plasmid Across Bacterial Species in Two Healthcare Facilities

Journal: Frontiers in Microbiology

Author(s): Lasek-Nesselquist, Erica

 

A common partitivirus infection in United States and Czech Republic isolates of bat white-nose syndrome fungal pathogen Pseudogymnoascus destructans

Journal: Scientific Reports

Author(s): Sui, Haixin; Masters, Paul; Chaturvedi, Sudha; Chaturvedi, Vishnu

 

Evaluation of an ensemble-based distance statistic for clustering MLST datasets using epidemiologically defined clusters of cyclosporiasis

Journal: Epidemiology & Infection

Author(s): Madison- Antenucci, Susan

 

Presence of Segmented Flavivirus Infections in North America

Journal: Emerging Infectious Diseases

Author(s): Kramer, Laura

 

The risk of malaria infection for travelers visiting the Brazilian Amazonian region: A mathematical modeling approach

Journal: Travel Medicine and Infectious Disease

Author(s): Conn, Jan

 

Ibrexafungerp: A Novel Oral Triterpenoid Antifungal in Development for the Treatment of Candida auris Infections

Journal: Antibiotics

Author(s): Chaturvedi, Vishnu; Chaturvedi, Sudha

 

JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo

Journal: Infectious Diseases

Author(s): Kramer, Laura; Li, Hongmin; Butler, David

 

Microglial mTOR is neuronal protective and anti-epileptogenic in the pilocarpine model of temporal lobe epilepsy

Journal: Journal of Neuroscience

Author(s): Mazurkiewicz, Joseph

 

Temporal and micro-spatial heterogeneity in transmission dynamics of co-endemic Plasmodium vivax and Plasmodium falciparum in two rural cohort populations in the Peruvian Amazon

Journal: The Journal of Infectious Diseases

Author(s): Conn, Jan

 

The optic nerve lamina region is a neural progenitor cell niche

Journal: PNAS

Author(s): Temple, Sally

 

Potency determination of ricin toxin using a monoclonal antibody-based competition assay

Journal: Journal of Immunological Methods

Author(s): Czajka, Timothy; Mantis, Nicholas

 

Profiles of urinary neonicotinoids and dialkylphosphates in populations in nine countries

Journal: Environment International

Author(s): Kannan, Kurunthachalam

 

Fetal exposure to phthalates and bisphenols and childhood general and organ fat

Journal: International Journal of Obesity

Author(s): Asimakopoulos, Alexandros; Martinez-Moral, Maria-Pilar; Kannan, Kurunthachalam

 

Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants

Journal: Journal of Biochemical and Molecular Toxicology

Author(s): Lawrence, David

 

Use of Functional MRI to Assess Effects of Deep Brain Stimulation Frequency Changes on Brain Activation in Parkinson Disease

Journal: Neurosurgery

Author(s): Shin, Damian

 

The Origin of COVID-19 and Why It Matters

Journal: The American Journal of Tropical Medicine and Hygiene

Author(s): Kramer, Laura

 

Development, phenotypes of immune cells in BTBR T+Itpr3tf/J mice

Journal: Cellular Immunology

Author(s): Lawrence, David

 

Multicenter evaluation of the NeuMoDx™ SARS-CoV-2 Test

Journal: Journal of Clinical Virology

Author(s): St. George, Kirsten

 

The Impact of Post-Analytical Tools on New York Screening for Krabbe Disease and Pompe Disease

Journal: International Journal of Neonatal Screening

Author(s): Caggana, Michele

 

SARS-CoV-2 antibody characterization in emergency department, hospitalized and convalescent patients by two semi-quantitative immunoassays

Journal: Clinica Chimica Acta

Author(s): Lee, William

 

Breathable, large-area epidermal electronic systems for recording electromyographic activity during operant conditioning of H-reflex

Journal: Biosensors & Bioelectronics

Author(s): Wolpaw, Jonathan

 

Zika Virus Infection Results in Biochemical Changes Associated With RNA Editing, Inflammatory and Antiviral Responses in Aedes albopictus

Journal: Frontiers in Microbiology

Author(s): Bialosuknia, Sean; Ciota, Alexander; Kramer, Laura

 

Quantifying and Characterizing Distributive Conjugal Transfer in Mycobacterium smegmatis

Journal: Methods in Molecular Biology

Author(s): Gray, Todd; Derbyshire, Keith

 

Multiplexed non-invasive tumor imaging of glucose metabolism and receptor-ligand engagement using dark quencher FRET acceptor

Journal: Theranostics

Author(s): Mazurkiewicz, Joseph

 

Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing

Journal: Nucleic Acids Research

Author(s): Belfort, Marlene

 

Endpoint and epitope-specific antibody responses as correlates of vaccine-mediated protection of mice against ricin toxin

Journal: Vaccine

Author(s): Mantis, Nicholas

 

Phylogenetic Network of Mitochondrial COI Gene Sequences Distinguishes 10 Taxa Within the Neotropical Albitarsis Group (Diptera: Culicidae), Confirming the Separate Species Status of Anopheles albitarsis H (Diptera: Culicidae) and Revealing a Novel Lineage, Anopheles albitarsis J

Journal: Journal of Medical Entomology

Author(s): Conn, Jan

 

Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development

Journal: Virus Research

Author(s): Li, Hongmin

 

Reversion to ancestral Zika virus NS1 residues increases competence of Aedes albopictus

Journal: PLOS Pathogens

Author(s): Kramer, Laura; Ciota, Alexander

 

Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo

Journal: Emerging Microbes & Infections

Author(s): Kramer, Laura; Butler, David; Li, Hongmin

 

Small-molecule antibiotics inhibiting tRNA regulated gene expression is a viable strategy for targeting Gram-positive bacteria

Journal: Antimicrobial Agents and Chemotherapy

Author(s): Schneider, Ryan; Lasek-Nesselquist, Erica; McDonough, Kathleen

 

Optimizing open data to support one health: best practices to ensure interoperability of genomic data from bacterial pathogens

Journal: One Health Outlook

Author(s): Wolfgang, William

 

A simple protein-based surrogate neutralization assay for SARS-CoV-2

Journal: JCI Insight

Author(s): McDonough, Kathleen

 

Divergent Mutational Landscapes of Consensus and Minority Genotypes of West Nile Virus Demonstrate Host and Gene-Specific Evolutionary Pressures

Journal: Genes

Author(s): Caldwell, Haley; Lasek-Nesselquist, Erica; Kramer, Laura; Ciota, Alexander

 

The Vector-Host-Pathogen Interface: The Next Frontier in the Battle Against Mosquito-Borne Viral Diseases?

Journal: Frontiers in Cellular and Infection Microbiology

Author(s): Ciota, Alexander; Kramer, Laura

 

Transcription termination and antitermination of bacterial CRISPR arrays

Journal: Elife

Author(s): Lasek-Nesselquist, Erica; Wade, Joseph

 

Contribution of Pulmonary CYP-mediated Bioactivation of Naphthalene to Airway Epithelial Injury in the Lung

Journal: Toxicological Sciences

Author(s): Kovalchuk, Nataliia; Zhang, Qing-Yu

 

In Vitro Activity of Manogepix against Multidrug-Resistant and Panresistant Candida auris from the New York Outbreak

Journal: Antimicrobial Agents and Chemotherapy

Author(s): Chaturvedi, Sudha; Chaturvedi, Vishnu

 

Host feeding patterns of Nyssorhynchus darlingi (Diptera: Culicidae) in the Brazilian Amazon

Journal: Acta Tropica

Author(s): Conn, Jan

 

Sensitization of Airway Epithelial Cells to Toxin-Induced Death by TNF Superfamily Cytokines

Journal: Methods in Molecular Biology

Author(s): Mantis, Nicholas

 

Isovaline efficacy in a rat pup model of infantile spasms

Journal: NeuroReport

Author(s): Shin, Damian

 

Increase in temperature enriches heat tolerant taxa in Aedes aegypti midguts

Journal: Scientific Reports

Author(s): Bialosuknia, M. Sean; Ciota, Alexander; Kramer, Laura

 

Serosurvey for dengue virus infection among pregnant women in the West Nile virus enzootic community of El Paso Texas

Journal: PLOS ONE

Author(s): Kramer, Laura

 

Genome Profiling for Aflatoxin B-1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B-1-Associated DNA Damage

Journal: G3-Genes | Genomes | Genetics

Author(s): Fasullo, Michael

 

Sites of vulnerability on ricin B chain revealed through epitope mapping of toxin-neutralizing monoclonal antibodies

Journal: PLOS ONE

Author(s): Poon, Amanda; Mantis, Nicholas

 

Heterotrimeric PCNA increases the activity and fidelity of Dbh, a Y-family translesion DNA polymerase prone to creating single-base deletion mutations

Journal: DNA Repair

Author(s): Wu, Yifeng; Pata, Janice

 

Transmission potential of Mayaro virus by Aedes albopictus, and Anopheles quadrimaculatus from the USA

Journal: Parasites & Vectors

Author(s): Ciota, Alexander; Kramer, Laura

 

Baloxavir treatment of oseltamivir‐resistant influenza A/H1pdm09 in two immunocompromised patients

Journal: Transplant Infectious Disease

Author(s): St. George, Kirsten

 

Roger Williams, CBE, 1931-2020

Journal: Hepatology

Author(s): Lee, William

 

Replacement of S14 protein in ribosomes of zinc-starved mycobacteria reduces spectinamide sensitivity

Journal: Antimicrobial Agents and Chemotherapy

Author(s): Agrawal, Rajendra; Ojha, Anil

 

Candida auris colonization after discharge to a community setting — New York City, 2017–2019

Journal: Open Forum Infectious Diseases

Author(s): Chaturvedi, Sudha

 

Vector Competence of Aedes albopictus Populations from the Northeastern United States for Chikungunya, Dengue, and Zika Viruses

Journal: The American Journal of Tropical Medicine and Hygiene

Author(s): Ciota, Alexander; Kramer, Laura

 

Drug repurposing approach to combating coronavirus: Potential drugs and drug targets

Journal: Medicinal Research Reviews

Author(s): Li, Hongmin

 

Targeting Crucial Host Factors of SARS-CoV-2

Journal: ACS Infectious Diseases

Author(s): Li, Hongmin

 

Performance evaluation of antibody-based point-of-care devices intended for the identification of immune responses to SARS-CoV-2

Journal: Diagnostic Microbiology and Infectious Disease

Author(s): McDonough, Kathleen; Lee, William

 

Disparities in Care Outcomes in Atlanta Between Black and White Men Who Have Sex With Men Living With HIV: Protocol for a Prospective Cohort Study Engagement

Journal: Nueroscience Letters

Author(s): Shin, Damian

 

Pan-resistant Candida auris: New York subcluster susceptible to antifungal combinations

Journal: Lancet Microbe

Author(s): Chaturvedi, Sudha

 

Bacterial group II intron genomic neighborhoods reflect survival strategies: hiding and hijacking

Journal: Molecular Biology and Evolution

Author(s): Belfort, Marlene

 

Genetic Characterization of Mumps Viruses Associated with the Resurgence of Mumps in the United States: 2015–2017

Journal: Virus Research

Author(s): St. George, Kirsten

 

Performance of ICD-10-CM diagnosis codes for identifying children with Sickle Cell Anemia

Journal: Health Services Research

Author(s): Caggana, Michele

 

Surface coatings alter transcriptional responses to silver nanoparticles following oral exposure

Journal: NanoImpact

Author(s): Chittur, Sridar

 

Emerging Tick-Borne Diseases

Journal: Clinical Microbiology Reviews

Author(s): Madison-Antenucci, Susan; Kramer, Laura

 

Caries and periodontitis associated bacteria are more abundant in human saliva compared to other great apes

Journal: Archives of Oral Biology

Author(s): Tenniswood, Martin; Chittur, Sridar

 

Toward point-of-care diagnostics of Candida auris

Journal: medRxiv

Author(s): Chaturvedi, Sudha; Chaturvedi, Vishnu

 

Activation of group 2 innate lymphoid cells alleviates aging-associated cognitive decline

Journal: Journal of Experimental Medicine

Author(s): Chittur, Sridar; Temple, Sally

 

West Nile Virus fidelity modulates the capacity for host cycling and adaptation

Journal: Journal of General Virology

Author(s): Janice Pata; Kramer, Laura; Ciota, Alexander

 

Integrated Arbovirus Surveillance Improves the Detection Onset of Zika Virus in Panama

Journal: The American Journal of Tropical Medicine and Hygiene

Author(s): Kramer, Laura

 

A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication

Journal: Toxins

Author(s): Mantis, Nicholas

 

Unique cell surface mannan of yeast pathogen Candida auris with selective binding to IgG

Journal: ACS Infectious Disease

Author(s): Chaturvedi, Vishnu

 

Human Adenovirus 7d Strains Associated with Influenza-Like Illness, New York, USA, 2017–2019

Journal: Emerging Infectious Diseases

Author(s): St. George, Kirsten

 

Optimizing Open Data to Support One Health: Best Practices to Ensure Interoperability of Genomic Data from Microbial Pathogens

Journal: Europe PMC

Author(s): Wolfgang, William

 

Group II intron as cold sensor for self-preservation and bacterial conjugation

Journal: Nucleic Acids Research

Author(s): Belfort, Marlene

 

Understanding, verifying and implementing Emergency Use Authorization molecular diagnostics for the detection of SARS-CoV-2 RNA

Journal: Journal of Clinical Microbiology

Author(s): St. George, Kirsten

 

Progression from remodeling to hibernation of ribosomes in zinc-starved mycobacteria

Journal: Proceedings of the National Academy of Sciences of the United States of America

Author(s): Ojha, Anil

 

Reply to Flannery, et al

Journal: Clinical Infectious Diseases

Author(s): St. George, Kristen

 

COVID-19 Testing, Epidemic Features, Hospital Outcomes, and Household Prevalence, New York State—March 2020

Journal: Clinical Infectious Diseases

Author(s): St. George, Kristen

 

Determination of Genomic Epidemiology of Historical Clostridium perfringens Outbreaks in New York State Using Two Web-based Platforms: National Center for Biotechnology Information-Pathogen Detection and FDA-GalaxyTrakr

Journal: Journal of Clinical Microbiology

Author(s): Wolfgang, William

 

Serologic Survey of Mosquito-Borne Viruses in Hunter-Harvested White-Tailed Deer (Odocoileus virginianus), New York State

Journal: The American Journal of Tropical Medicine and Hygiene

Author(s): Kramer, Laura

2019

Joachim Frank's Binding with the Ribosome

Journal: Structure

Author(s): Agrawal, Rajendra

 

Structural insights into unique features of the human mitochondrial ribosome recycling

Journal: Proceedings of the National Academy of Sciences of the United States of America

Author(s): Agrawal, Rajendra

 

Structure of Human Mitochondrial Translation Initiation Factor 3 Bound to the Small Ribosomal Subunit

Journal: iScience

Author(s): Agrawal, Rajendra

 

Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanism

Journal: Chemical Communications

Author(s): Banavali, Nilesh

 

The Mechanism of Cholesterol Modification of Hedgehog Ligand

Journal: Journal of Computational Chemistry

Author(s): Banavali, Nilesh

 

Biocatalysis, Protein Engineering, and Nanobiotechnology

Journal: Biotechnology and Bioengineering

Author(s): Belfort, Marlene

 

Co-ordinated enzyme catalysis: Designing a cell-free system

Journal: Abstracts of Papers of the American Chemical Society

Author(s): Belfort, Marlene

 

Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools

Journal: Cold Spring Harbor Perspectives in Biology

Author(s): Belfort, Marlene

 

Mechanism of single-stranded DNA activation of recombinase intein splicing

Journal: Biochemistry

Author(s): Belfort, Marlene

 

Structure of an engineered intein reveals thiazoline ring and provides mechanistic insight

Journal: Biotechnology and Bioengineering

Author(s): Belfort, Marlene

 

Preconception serum lipids and lipophilic micronutrient levels are associated with live birth rates after IVF

Journal: Reproductive BioMedicine Online

Author(s): Bloom, Michael

 

Laboratory Analysis of an Outbreak of Candida auris in New York from 2016 to 2018-Impact and Lessons Learned

Journal: Journal of Clinical Microbiology

Author(s): Chaturvedi, Sudha; Blog, Debra

 

Assessment of Environmental and Occupational Exposure while Working with Candida auris a Multidrug Resistant (MDR) Fungus in the Animal Facility

Journal: Journal of Occupational and Environmental Hygiene

Author(s): Chaturvedi, Sudha; DeJesus, Magdia

 

MycopathologiaGENOMES: The New ‘Home’ for the Publication of Fungal Genomes

Journal: Mycopathologia

Author(s): Chaturvedi, Vishnu

 

Talaromycosis (Penicilliosis) Due to Talaromyces (Penicillium) marneffei: Insights into the Clinical Trends of a Major Fungal Disease 60 Years After the Discovery of the Pathogen

Journal: Mycopathologia

Author(s): Chaturvedi, Vishnu

 

Impact on Glioblastoma U87 Cell Gene Expression of a Carborane Cluster-Bearing Amino Acid: Implications for Carborane Toxicity in Mammalian Cells

Journal: ACS Chemical Neuroscience

Author(s): Chittur, Sridar

 

HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting

Journal: PNAS

Author(s): Chittur, Sridar

 

Mating enhances expression of hormonal and trophic factors in the midbrain of female rat

Journal: Gene Expression Omnibus

Author(s): Chittur, Sridar

 

Compartmentalized effects of aging on group 2 innate lymphoid cell development and function

Journal: Aging Cell

Author(s): Chittur, Sridar

 

The role of co-infection and swarm dynamics in arbovirus transmission

Journal: Virus Research

Author(s): Ciota, Alexander

 

The Role of Temperature in Transmission of Zoonotic Arboviruses

Journal: Viruses

Author(s): Ciota, Alexander

 

Genetic diversity of Nyssorhynchus (Anopheles) darlingi related to biting behavior in western Amazon

Journal: Parasites and Vectors

Author(s): Conn, Jan

 

High-accuracy detection of malaria vector larval habitats using drone-based multispectral imagery

Journal: PLOS Neglected Tropical Diseases

Author(s): Conn, Jan

 

Higher risk of malaria transmission outdoors than indoors by Nyssorhynchus darlingi in riverine communities in the Peruvian Amazon

Journal: Parasites and Vectors

Author(s): Conn, Jan

 

Malaria vector species in Amazonian Peru co-occur in larval habitats but have distinct larval microbial communities

Journal: PLOS Neglected Tropical Diseases

Author(s): Conn, Jan

 

Minimal genetic differentiation of the malaria vector Nyssorhynchus darlingi associated with forest cover level in Amazonian Brazil

Journal: PLoS One

Author(s): Conn, Jan

 

Regional variation in life history traits and plastic responses to temperature of the major malaria vector Nyssorhynchus darlingi in Brazil

Journal: Scientific Reports

Author(s): Conn, Jan

 

Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil

Journal: Malaria Journal

Author(s): Conn, Jan

 

Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region

Journal: Lancet Infectious Diseases

Author(s): Conn, Jan

 

Candida albicans Elicits Pro-Inflammatory Differential Gene Expression in Intestinal Peyer’s Patches

Journal: Mycopathologia

Author(s): DeJesus, Magdia

 

Dectin‐2‐mediated signaling triggered by the cell wall polysaccharides of Cryptococcus neoformans

Journal: Microbiology and Immunology

Author(s): DeJesus, Magdia

 

Polydopamine Coating of Glucan Particles Increases Uptake into Peyer's Patches

Journal: ACS Applied Bio Materials

Author(s): DeJesus, Magdia

 

Setting off the Alarms: Candida albicans Elicits Pro-Inflammatory Differential Gene Expression in Intestinal Peyer's Patches

Journal: Mycopathologia

Author(s): DeJesus, Magdia

 

A novel chemical lysis method for maximum release of DNA from difficult-to-lyse bacteria

Journal: Microbial Pathogenesis

Author(s): Egan, Christina

 

Botulism Outbreak Associated with Home-Canned Peas - New York City, 2018

Journal: MMWR

Author(s): Egan, Christina

 

Molecular Characterization of Clostridium botulinum Harboring the bont/B7 Gene

Journal: Foodborne Pathogens and Disease

Author(s): Egan, Christina

 

Mycobacterial SigA and SigB Cotranscribe Essential Housekeeping Genes during Exponential Growth

Journal: MBIO

Author(s): Ghosh, Pallavi

 

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing

Journal: Cell Reports

Author(s): Glaser, Robert

 

A phylogenomic approach to clarifying the relationship of Mesodinium within the Ciliophora: a case study in the complexity of mixed-species transcriptome analyses

Journal: Genome Biology and Evolution

Author(s): Lasek-Nesselquist, Erica

 

The cationic (calcium and lead) and enzyme conundrum

Journal: Journal of Toxicology and Environmental Health Part B-Critical Reviews

Author(s): Lawrence, David

 

Contributions of Hepatic and Intestinal Metabolism to the Disposition of Niclosamide, a Repurposed Drug with Poor Bioavailability

Journal: Drug Metabolism and Disposition

Author(s): Li, Hongmin

 

Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation

Journal: Nature Communications

Author(s): Li, Hongmin

 

Antigen Engineering Approaches for Lyme Disease Vaccines

Journal: Bioconjugate Chemistry

Author(s): Lin, Yi-Pin

 

Further Insights Into the Interactions of Human and Animal Complement Regulator Factor H With Viable Lyme Disease Spirochetes

Journal: Frontiers in Veterinary Science

Author(s): Lin, Yi-Pin

 

Outer surface protein polymorphisms linked to host-spirochete association in Lyme borreliae

Journal: Molecular Microbiology

Author(s): Lin, Yi-Pin

 

An Intranasally Administered Antibody Cocktail Prevents Ricin Toxin-Induced Lung Inflammation and Alveolar Macrophage Death

Journal: The Journal of Immunology

Author(s): Mantis, Nicholas

 

Rescue of rhesus macaques from the lethality of aerosolized ricin toxin

Journal: JCI Insight

Author(s): Mantis, Nicholas

 

Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes

Journal: Journal of Leukocyte Biology

Author(s): Mantis, Nicholas

 

TNF Family Cytokines Induce Distinct Cell Death Modalities in the A549 Human Lung Epithelial Cell Line when Administered in Combination with Ricin Toxin

Journal: Toxins

Author(s): Mantis, Nicholas

 

Cardiomyocyte orientation modulated by the Numb family proteins–N-cadherin axis is essential for ventricular wall morphogenesis

Journal: PNAS

Author(s): Mazurkiewicz, Joseph

 

Fast fit-free analysis of complex fluorescence lifetime imaging via deep learning

Journal: PNAS

Author(s): Mazurkiewicz, Joseph

 

Fluorescent Lifetime Imaging improved via Deep Learning

Journal: Novel Techniques in Microscopy

Author(s): Mazurkiewicz, Joseph

 

Microvascular pathology in Friedreich cardiomyopathy

Journal: Histology and Histopathology

Author(s): Mazurkiewicz, Joseph

 

Multiplexed Fluorescence Lifetime in vivo FRET Imaging using a Dark Quencher

Journal: Optical Molecular Probes, Imaging and Drug Delivery

Author(s): Mazurkiewicz, Joseph

 

Discovery of Small-Molecule Antibiotics against a Unique tRNA-Mediated Regulation of Transcription in Gram-Positive Bacteria

Journal: Chemmedchem

Author(s): McDonough, Kathleen

 

Early life adversity blunts responses to pioglitazone in depressed, overweight adults

Journal: European Psychiatry

Author(s): McEwen, Bruce

 

Parsing the Hippocampus in Depression: Chronic Stress, Hippocampal Volume, and Major Depressive Disorder

Journal: Biological Psychiatry

Author(s): McEwen, Bruce

 

A FRET-Based Fluorogenic Trehalose Dimycolate Analogue for Probing Mycomembrane-Remodeling Enzymes of Mycobacteria

Journal: ACS OMEGA

Author(s): Ojha, Anil

 

Adaptation of Mycobacterium tuberculosis to biofilm growth is genetically linked to drug tolerance

Journal: Antimicrobial Agents and Chemotherapy

Author(s): Ojha, Anil

 

IFCC Working Group Recommendations for Assessing Commutability Part 3: Using the Calibration Effectiveness of a Reference Material

Journal: Clinical Chemistry

Author(s): Rej, Robert

 

Impact of testosterone assay standardization efforts assessed via accuracy-based proficiency testing

Journal: Clinical Biochemistry

Author(s): Rej, Robert

 

A quantitative method for evaluating cortical responses to electrical stimulation

Journal: Journal of neuroscience methods

Author(s): Schalk, Gerwin

 

Mouse Models Reveal Role of T-Cytotoxic and T-Reg Cells in Immune Response to Influenza: Implications for Vaccine Design

Journal: Viruses-Basel

Author(s): Sell, Stewart

 

T-bet optimizes CD4 T-cell responses against influenza through CXCR3-dependent lung trafficking but not functional programming

Journal: Mucosal Immunology

Author(s): Sell, Stewart

 

Functional MRI Signature of Chronic Pain Relief From Deep Brain Stimulation in Parkinson Disease Patients

Journal: Neurosurgery

Author(s): Shin, Damian

 

Advancing the Public Health Laboratory System Through Partnerships

Journal: Public Health Reports

Author(s): St. George, Kirsten

 

Detection and Characterization of Influenza B Virus with Reduced Neuraminidase Susceptibility in a Stem Cell Transplant Recipient

Journal: Open Forum Infectious Diseases

Author(s): St. George, Kirsten

 

Emergence and re-emergence of respiratory adenoviruses in the United States

Journal: Current Opinion in Virology

Author(s): St. George, Kirsten

 

LB15. Measles Outbreak in New York State (NYS) Outside of New York City, 2018–2019

Journal: Open Forum Infectious Diseases

Author(s): St. George, Kirsten

 

LB16. The Role of Adults in the Measles Outbreak in New York State Outside of New York City, 2018–2019

Journal: Open Forum Infectious Diseases

Author(s): St. George, Kirsten

 

New York State Emergency Preparedness and Response to Influenza Pandemics 1918-2018

Journal: Tropical Medicine Infectious Disease

Author(s): St. George, Kirsten

 

Drug resistance mutations and viral load in human immunodeficiency virus type 2 and dual HIV-1/HIV-2 infected patients in Ghana

Journal: Medicine

Author(s): Styer, Linda

 

Three years of shared service HIV-1 and HIV-2 nucleic acid testing for public health laboratories: worthwhile for HIV-1 but not for HIV-2

Journal: Sexually Transmitted Diseases

Author(s): Styer, Linda

 

High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy

Journal: Nature Communications

Author(s): Sui, Haixin

 

Liquid chromatography-tandem mass spectrometry analysis of 17-hydroxyprogesterone in dried blood spots revealed matrix effect on immunoassay

Journal: Analytical and Bioanalytical Chemistry

Author(s): Tavakoli, Norma

 

Heterogeneous Expression of SDF1 Retains Actively Proliferating Neural Progenitors in the Capillary Compartment of the Niche

Journal: Stem Cell Research

Author(s): Temple, Sally

 

Stem Cell Scientists Answer the Question, "Why Is It Important to You to Support Fetal Tissue Research?''

Journal: Stem Cell Reports

Author(s): Temple, Sally

 

Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material

Journal: Investigative Ophthalmology & Visual Science

Author(s): Temple, Sally

 

Identifying Windows of Susceptibility by Temporal Gene Analysis

Journal: Scientific Reports

Author(s): Temple, Sally; Boles, Nathan

 

A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies

Journal: Stem Cell Reports

Author(s): Temple, Sally; Butler, David

 

Greater aortic stiffness is associated with renal dysfunction in participants of the ELSA-Brasil cohort with and without hypertension and diabetes

Journal: PLOS One

Author(s): Tenniswood, Martin

 

Prostate carcinoma in African-Americans has miRNA expression and biological markers for aggressive disease

Journal: Journal of Clinical Oncology

Author(s): Tenniswood, Martin

 

Starch nanoparticles for delivery of the histone deacetylase inhibitor cg-1521 in breast cancer treatment

Journal: International Journal of Nanomedicine

Author(s): Tenniswood, Martin

 

Concerns about “Stress-Induced MazF-Mediated Proteins in Escherichia coli”

Journal: American Society for Microbiology

Author(s): Wade, Joseph

 

Severe oral mucositis (SOM) mitigation by genetically modified lactococcus lactis bacteria (LLB) producing human trefoil factor 1 (hTFF1; AG013) in patients being treated with concomitant chemoradiation (CRT) for oral and oropharyngeal cancers (OCOPC)

Journal: Annals of Oncology

Author(s): Wade, Joseph

 

High-throughput determination of in vivo DNA sequence preferences for Cas protein binding using Library-ChIP

Journal: Methods in Enzymology

Author(s): Wade, Joseph

 

PulseNet and the Changing Paradigm of Laboratory-Based Surveillance for Foodborne Diseases

Journal: Public Health Reports

Author(s): Wolfgang, William

 

Impact of Candida auris infection in a neutropenic murine model

Journal: Antimicrobial Agents and Chemotherapy

Author(s): DeJesus, Magdia

 

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

Journal: Nature Chemistry

Author(s): Kramer, Laura

 

The vector ecology of introduced Culex quinquefasciatus populations, and implications for future risk of West Nile virus emergence in the Galápagos archipelago

Journal: Medical and Veterinary Entomology

Author(s): Kramer, Laura

 

Glycosaminoglycan Compositional Analysis of Relevant Tissues in Zika Virus Pathogenesis and in Vitro Evaluation of Heparin as an Antiviral against Zika Virus Infection

Journal: Biochemistry

Author(s): Kramer, Laura

 

Analysis of Protein-Protein Interactions by Split Luciferase Complementation Assay

Journal: Current Protocols in Toxicology

Author(s): Li, Hongmin

 

Impact of Mycobacterial Biofilms on Public Health

Journal: Connections Between Ecology and Infectious Disease

Author(s): Ojha, Anil

 

Screening and optimization of potential injection vehicles for storage of retinal pigment epithelial stem cell before transplantation

Journal: Journal of Tissue Engineering and Regenerative Medicine

Author(s): Temple, Sally

 

Why we need fetal tissue research

Journal: Science

Author(s): Temple, Sally

 

Optimizing intracellular antibodies (intrabodies/nanobodies) to treat neurodegenerative disorders

Journal: Neurobiology of Disease

Author(s): Messer, Anne; Butler, David

 

Vector Competence of Aedes caspius and Ae. albopictus Mosquitoes for Zika Virus, Spain

Journal: Emerging Infectious Diseases

Author(s): Ciota, Alexander; Kramer, Laura

 

H-reflex conditioning during locomotion in people with spinal cord injury

Journal: Journal of Physiology-London

Author(s): Thompson, Aiko; Wolpaw, Jonathan

 

Cisplatin mice from challenge of Cryptococcus neoformans by targeting the Prp8 intein

Journal: Emerging Microbes and Infections

Author(s): Chaturvedi, Sudha; Belfort, Marlene; Li, Hongmin

 

Mouse Strain and Sex-Dependent Differences in Long-Term Behavioral Abnormalities and Neuropathogies after Developmental Zika Infection

Journal: Journal of Neuroscience

Author(s): Snyder- Keller, Abigail; Kramer, Laura; Bolivar, Valerie

 

REPLY TO TOBIASSON ET AL.: Zinc depletion is a specific signal for induction of ribosome hibernation in mycobacteria

Journal: Proceedings of the National Academy of Sciences of the United States

Author(s): Wade, Joseph; Gray, Todd; Derbyshire, Keith; Agrawal, Rajendra; Ojha, Anil

 

Multidrug-Resistant Candida auris Isolates from New York Hospitals and Healthcare Facilities are Susceptible to Antifungal Combinations

Journal: Open Forum Infectious Diseases

Author(s): Chaturvedi, Sudha; Chaturvedi, Vishnu

 

Insights Into the Evolution of Staphylococcus aureus Daptomycin Resistance From an in vitro Bioreactor Model

Journal: Frontiers in Microbiology

Author(s): Pata, Janice; McDonough, Kathleen

 

Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections

Journal: Clinical Science

Author(s): St. George, Kirsten; Kramer, Laura

 

Adaptation of Rabensburg virus (RBGV) to vertebrate hosts by experimental evolution

Journal: Virology

Author(s): Kramer, Laura; Ciota, Alexander

 

Blood treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts

Journal: Cell Microbiology

Author(s): Kramer, Laura; Lin, Yi-Pin

 

Evolutionary dynamics and molecular epidemiology of West Nile virus in New York State: 1999-2015

Journal: Virus Evolution

Author(s): Kramer, Laura; Ciota Alexander

 

Introduction, Spread and Establishment of West Nile Virus in the Americas

Journal: Journal of Medical Entomology

Author(s): Kramer, Laura; Ciota Alexander

 

General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog Autoprocessing

Journal: Journal of the American Chemical Society

Author(s): Li, Hongmin; Banavali, Nilesh

 

Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing

Journal: Plos Biology

Author(s): Banavali, Nilesh; Belfort, Marlene; Li, Hongmin

 

Bi-Functional Anti-Tau Polypeptides and Use Thereof

Journal: US

Author(s): Temple, Sally; Messer, Anne; Butler, David

 

Three-dimensional architecture of epithelial primary cilia

Journal: Proceedings of the National Academy of Sciences of the United States of America

Author(s): Sui, Haixin

 

Vitamin D and testosterone co-ordinately modulate intracellular zinc levels and energy metabolism in prostate cancer cells

Journal: Journal of Steroid Biochemistry and Molecular Biology

Author(s): Tenniswood, Martin

 

Seasonal temperatures and hydrological conditions improve the prediction of West Nile virus infection rates in Culex mosquitoes and human case counts in New York and Connecticut

Journal: PLOS One

Author(s): McDonough, Kathleen; Conn, Jan; Kramer, Laura

 

Biomonitoring of populations in Western New York at risk for exposure to Great Lakes contaminants

Journal: Environmental Research

Author(s): Rej, Robert

Meet Our Students

Lanilei Doctora
Lanilei Doctora headshot

 

Why did you choose to do an MS in BMS?
It’s a versatile degree where I could get exposure to the vast amount of lab techniques I would need to pursue a career in research and development. In addition, the program is associated with NYSDOH, meaning I’d have access to significant resources in biomedical sciences.

What are you investigating in the lab?
My project uses yeast as model organism to investigate the role of the Ty1 retrotransposon (a mobile genetic element) on spindle pole body inheritance. The Ty1 retrotransposon is structurally and functionally related to retroviruses and the spindle pole body is analogous to the centrosome in mammals. The goal is to gain insight on the mechanism behind how retrotransposons affect stem cell differentiation. 

What are your career goals?
My goal is to utilize my years of industry experience as well as my master’s degree to pursue a position as a research associate within a biopharmaceutical company, and eventually become a research scientist. 

 

Peer Mentors

Amber Frye
Amber Frye standing in front of mountains on a winter day

 

Fifth year PhD candidate Amber Frye is from Cleveland, Ohio. She completed her undergraduate degree in Utah where she worked as a Laboratory Technician and a Research Assistant. Amber is now working in Dr. Nicholas Mantis's lab in the Wadsworth Center. Currently, Amber's research interest focuses on antibody-mediated mechanisms of protection against Lyme borrelia, the bacterium responsible for Lyme disease, which is endemic in the state of New York. The project involves the identification and characterization of linear and conformational B cell epitopes of a Lyme borreliae outer surface protein, and which those epitopes confer protection. Outside of her academic interests, Amber's hobbies and interests include hiking or kayaking with her dog Lucie, baseball, and reading microbial pathogen books.

Kayla Simanek
Kayla Simanek sitting on a rock overlooking a lake and mountains in the background

 

Kayla completed her master's degree in microbiology at the University of Wisconsin, Milwaukee. After finishing her degree, she was selected for the Antimicrobial Resistance Laboratory Network Fellowship through the Association of Public Health Laboratories and the CDC. Kayla helped the Virginia State Public Health Laboratory establish a workflow for next-generation sequencing of antibiotic resistant clinical isolates and participated in SARS-CoV-2 sample testing. She joined the Paczkowski lab and studies Pseudomonas aeruginosa quorum sensing pathways. Kayla is excited to begin investigating quorum sensing of clinical P. aeruginosa isolates. Kayla likes films... both biological and on the big screen.

Sam Lindberg
Sam Lindberg sitting next to plants on a sunny day

 

Third year PhD candidate Sam Lindberg is from Altamont, New York. Because she went directly from her undergraduate degree at Worcester Polytechnic Institute to the PhD program, Sam understands the challenges that students can face with that transition. She established the peer mentorship program to connect new students with more experienced counterparts with the goal of helping them feel welcome and succeed. She also serves as a student representative on the Executive Committee for the BMS department. Sam has always been interested in infectious disease, and she is currently working in Dr. Nicholas Mantis' lab studying Salmonella. Currently, Sam's research interest focuses on identifying the signal transduction pathways in Salmonella Typhimurium that are involved in the response to monoclonal antibody treatment. In her free time, Sam enjoys hiking around Thacher State Park, baking, and cooking tasty vegetarian dishes. She also loves to paint and read, especially non-fiction, mystery and sci-fi.

Rachel Lange
Rachel Lange headshot

 

Rachel Lange is a 2nd year PhD student who is originally from the Virginia Beach area. She got her undergraduate degree in biochemistry from Syracuse University where she worked in an immunology laboratory at SUNY Upstate Medical University and an ecology laboratory at SUNY ESF. Rachel's inherent curiosity and love for the natural world drew her to science and she sought to combine her immunology and ecology background to study the dynamics of emerging vector-borne diseases at UAlbany. Her current work at the Arbovirology Laboratories directed by Alex Ciota, focuses on characterizing tick-borne viruses and investigating viral genetic correlates of host-specificity. In the future, she would like to use her research to educate populations in high-risk areas for zoonotic disease spillovers on sustainable prevention measures and animal health. Outside of the lab you can usually find Rachel in the woods - most likely on a paddleboard.

Tristan Nowak
Tristan Nowak dressed in a lab coat sitting in a laboratory setting

 

Third year PhD candidate Tristan Nowak is from Chittenango, New York. Before joining Dr. Yi-Pin Lin’s lab at the Wadsworth Center, he obtained his undergraduate degree at Syracuse University and a Master of Science at the University of Florida. Currently, Tristan’s research focuses on identifying mechanisms contributing to Borrelia burgdorferi sensu lato (Lyme disease bacterium) survival in ticks. This work expands our understanding of how pathogens interact with their vectors, or hosts. It also explores the redundancy of functional proteins that contribute in an overall synergistic manner during tick colonization. These concepts can be exploited to establish reservoir-based preventive strategies against the tick infection cycle by reducing their prevalence in the field, abating transmission, and improving human health. Outside of his academic interests, Tristan volunteers with COVID testing and somehow finds time to build Adirondack chairs. His favorite outdoor activities are hiking, kayaking, biking, hockey. He is a favorite with local random dogs who say he gives very good head scratches.

Ali Ropri
Ali Ropri standing in front of UAlbany Health Sciences Campus

 

PhD candidate Ali Ropri is from Latham, New York. He completed his undergrad at Siena College. Ali is now working in Dr. Herschkowitz’s lab at the Cancer Research Center. Currently, Ali’s research interest focuses on understanding the mechanism driving indolent ductal carcinoma in situ lesions to become aggressive breast cancer.  Outside of his academic interests, Ali’s hobbies include hiking all national parks in the US, cricket, and playing FIFA with friends.

Rachel Fay
Rachel Fay headshot

 

PhD candidate Rachel Fay is from Chatham, NY. She completed her undergraduate degree at SUNY Potsdam and now works in the New York State Arbovirus Lab under the guidance of Dr. Alexander Ciota. Rachel studies the influence of temperature on flavivirus evolution, fitness, and vector-virus interactions. Her work investigates the question of whether increases in temperature drive the emergence of high fitness flavivirus strains. Additionally, she is interested in how increases in temperature impact mosquito biology and vector-virus interactions that may facilitate increased transmissibility of mosquito-borne diseases under climate change. Outside of her academic interests, Rachel's hobbies and interests include baking, running, and musicals.