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Department Chair and Professor
College of Arts and Sciences
Design and discovery of novel molecules to regulate protein function in nerve systems; ALS; neurodegenerative diseases
Campus phone: (518) 591-8820
Campus email: email@example.com
Chemistry Professor Li Niu explores the design and discovery of novel molecules to regulate protein function in nerve systems, using combinatorial libraries, biosensor, molecular biology, and biophysical methods.
Niu's lab conducts research on cells that harbor the special family of proteins called glutamate ion channel receptors, which are indispensable to brain function such as memory and learning.
Abnormal function of these proteins is implicated in neurological disorders and diseases like Amyotrophic Lateral Sclerosis (ALS) and stroke. Niu's research seeks to find inhibitors as potential drug candidates for treatments of these diseases.
His long-term goal is to understand the structure and function of these receptors, and to design better inhibitors as potential drug candidates for new therapies.
Niu's work has been supported by grants from the National Institutes of Health, the Department of Defense and the Muscular Dystrophy Association.