Roxana Moslehi

Roxana Moslehi
Associate Professor
Epidemiology & Biostatistics
Education

Postdoctoral Fellowship [Genetic Epidemiology and Biostatistics], Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), NIH

Ph.D. [Medical Genetics], University of British Columbia

M.Sc. [Medical Genetics], University of British Columbia

B.Sc.(Honours) [Cell & Developmental Biology], University of British Columbia

About

Research Interests:

The overall objectives of my research studies are to identify genetic and environmental determinants of complex disorders and to quantify their effects. I have expertise in designing family-based and population-based genetic epidemiologic investigations and in statistical analysis of genetic and epidemiologic data. As part of my studies, I have also conducted genetic counseling for hereditary cancer susceptibility. The methodologies currently employed in my laboratory include family studies, case-control studies, analysis of genome-wide association studies (GWAS), candidate-gene and whole-genome linkage analyses, and gene expression (gene chip) array and transcriptome analyses. Various malignant and pre-malignant conditions have been the focus of my research. I have been studying cancer risks associated with mutations in the DNA repair genes for a number of years. Based on recent clinical observations, I also initiated several studies to gain insight into the biologic mechanisms which underlie the association between DNA repair and transcription gene abnormalities in the fetus and increased risk of gestational complications.

 

Frequently teaches:

  • “Cancer Epidemiology” (EPI 604)
  • “Genetic Epidemiology” (EPI 624)
  • “Masters Seminars in Epidemiology” (EPI 602)
  • “Principles and Methods of Epidemiology II” (EPI 502)
  • "Principles and Methods of Epidemiology I" (EPI 501)
  • "Basic Principles and Methods of Epidemiology" (EPI 500)
  • “Molecular Epidemiology” (EPI 512)
  • "Introduction to Genetic Epidemiology” (EPI 512)