The training program has developed a curriculum based on the national need for interdisciplinary trianing, in the general area of RNA in Health and Disease, and to prepare students for jobs in academia, industry, government, communication and elsewhere.

First Year
Students in the program completely a series of core courses required of their home departments, followed by courses on specific topics of interest in subsequent years. Students also undertake research rotations in three labs during their first year and then select a research advisor. Students will be selected for the training program in the Spring (second) semester of their first year. If there is an Albany Conversation in Biiomolecular Stereodynamics, a biennial international conference, scheduled that summer, they will be required to attend. In subsequent summers, they will be required to present their research at this conference. Another summer option is the Writing Workshop, which is held in Saratoga Springs on the Skidmore College Campus.

Second Year
During their second year, trainees will take the two-semester RNA Flagship course, and at least one course in Mathematical fluency. Other departmental electives can be selected from this list.

Third Year
At this point students can opt for the Entrepreneurship course and they will be required totake this course unless they have chosen to take the Writing Workshop. Throughout their training students will attend both their departmental and T32-specific seminars.

Trainees, who are supported by teaching assistantships during their first years, will receive ample opportunities to teach. They can elect to have classroom and/or laboratory teaching experiences. During their research training they will also be called upon to supervise undergraduates, allowing them to develop mentoring skills, as they themselves are being mentored.