Joseph T. Wade
Associate Professor
College of Integrated Health Sciences
Department of Biomedical Sciences
The RNA Institute
Contact
Education
PhD in Biochemistry, University of Birmingham, UK
Postdoctoral training, Harvard Medical School
About
Affiliation: Wadsworth Center, New York State Department of Health
Dr. Wade’s research focuses on processes involving nucleic acids in bacteria such as Escherichia coli, Salmonella enterica, and Mycobacterium tuberculosis. Current areas of interest include transcription regulation, mechanisms of translation initiation, small protein function, and CRISPR-Cas immunity. Much of Dr. Wade’s research involves genome-scale and high-throughput approaches that use next-generation sequencing.
Research
Joseph T. Wade on Google Scholar
Research Interests
- Bacterial gene regulation
- CRISPR-Cas immunity mechanisms in bacteria
Research concentrations
- Infection & Immunity
- Genes & Genomes
Publications
- Adams, P. P., Baniulyte, G., Esnault, C., Chegireddy, K., Singh, N., Monge, M., Dale, R. K., Storz, G. and Wade, J. T. (2021). Regulatory roles of Escherichia coli 5' UTR and ORF-internal RNAs detected by 3' end mapping. eLife, 10:e62438.
- Stringer, A. M., Baniulyte, G., Lasek-Nesselquist, E., Seed, K. D. and Wade, J. T. (2020). Nus Factors Prevent Premature Transcription Termination of Bacterial CRISPR Arrays. eLife, 9, e58182.
- Baniulyte, G. and Wade, J. T. (2019). An antibiotic-sensing leader peptide regulates translation and premature Rho-dependent transcription termination of the topAI gene in Escherichia coli.