Ryan Thurman

Areas of Interest

• Forensic Chemistry
• Forensic Toxicology
• Pharmaceutical Analogues
• Protein interactions with small molecules

Research

Ryan received his PhD from the University of Arkansas in Chemistry. In 2013 he received the Lineberger Comprehensive Cancer Center fellowship at the University of North Carolina, Chapel Hill. While at UNC Ryan worked in the Biochemistry and Biophysics Department researching KRAS signaling, protein dynamics and small molecule inhibitors using multi-dimensional NMR. While at UNC Ryan also taught Chemistry and Biochemistry. Ryan joined the University at Albany in January 2018 and he is teaching forensic chemistry in the MS Forensic Biology program. Ryan’s research interests are focused on investigating the toxicology and forensic chemistry of emerging pharmaceutical analogues. 

Publications

• Atypical KRAS G12R mutant is impaired in PI3K signaling and micropinocytosis”. G. Aaron Hobbs, Nicole M. Baker, Anne M. Miermont, Ryan D. Thurman, Mariaelena Pierobon, Timothy H. Tran, Andrew Anderson, Andrew M. Waters, J. Nathaniel Diehl, Kirsten L. Bryant, Dominic Esposito, Sharon L. Campbell, Emanuel F. Petricoin, III, Dhirendra K. Simanshu, Udo Rudloff, Adrienne D. Cox & Channing J. Der. (2018) Manuscript submitted for publication.
• RAS ubiquitylation modulates effector interactions.� Thurman R, Siraliev-Perez E, Campbell SL.Small GTPases. (2017) Nov 29, 2017:1-6. doi: 10.1080/21541248.2017.1371267. PMID:29185849
• Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factor.� Jayanthi S, Kathir KM, Rajalingam D, Furr M, Daily A, Thurman R, Rutherford L, Chandrashekar R, Adams P, Prudovsky I, Kumar TK. (2014) Biochim. Biophys. Acta. 2014; 1844(12): 2155-65. PMID: 25224745
• In-Cell NMR Spectroscopy-In vivo�monitoring of the structure, dynamics, folding, and interactions of proteins at atomic resolution.” Kumar TK, Thurman R, Jayanthi S.J. Anal Bioanal Tech (2013) Jan 2, 2013;4(1):e112. PMID:23956945
• "Molecular basis for the Kallmann syndrome-linked fibroblast growth factor receptor mutation.” Thurman RD, Kathir KM, Rajalingam D, Kumar TK. (2012) Biochem Biophys Res Commun. 2012 Aug 31;425(3):673-8. doi: 10.1016/j.bbrc.2012.07.104. Epub 2012 Jul 27. PMID:22842457.