Soma Dash

Soma Dash

Assistant Professor
Department of Biological Sciences
The RNA Institute

PhD, University of Delaware
Bachelor of Technology in Biotechnology, National Institute of Technology, Raipur, India

Soma Dash

Dash Lab

Areas of Interest:

  • Developmental and Molecular Biology
  • Craniofacial Development
  • Transcription and post-transcription gene regulation


  1. Modelski M., Menlah G., Wang Y., Dash S., Wu K., Galileo D.S., and Martin-DeLeon P.A. (2014) Hyaluronidase 2: A Novel Germ Cell Hyaluronidase with Epididymal Expression and Functional Roles in Mammalian Sperm. Biology of Reproduction; 91(5):109 1-11. View in: Pubmed
  2. Smith M.A., Michael S.R., Aravindan G. R., Dash S., Shah I., Galileo D.S., Martin-DeLeon P.A. (2015) Anatase Titanium Dioxide Nanoparticles in Mice: Evidence for Induced Structural and Functional Sperm Defects after Short-, but not Long-, term Exposure. Asian Journal of Andrology; 17(2):261-8. View in: Pubmed
  3. Dash S., Dang C.A., Beebe D.C., Lachke S.A. (2015) Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Development Dynamics; 244(10):1313-27. View in: Pubmed
  4. Agrawal S.A., Anand D., Siddam A.D., Kakrana A., Dash S., Scheiblin D.A., Dang C.A., Terrell A.M., Waters S.M., Singh A., Motohashi H., Yamamoto M., Lachke S.A. (2015) Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract. Human Genetics; 134(7):717-35. View in: Pubmed
  5. Srivastava R., Budak G., Dash S., Lachke S.A., Janga S.C. (2017) Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations. Scientific Reports; 7(1):115732. View in: Pubmed
  6. Budak G., Dash S., Srivastava R., Lachke S.A., Janga S.C. (2018) Express: A database of transcriptome profiles encompassing known and novel transcripts across multiple development stages in eye tissues. Experimental Eye Research; 168:57-66. View in: Pubmed
  7. Dash S., Brastorm L.K., Patel S.D., Scott C.A., Slusarksi D. C., Lachke S.A. (2020) The master transcription factor SOX2, mutated in anophthalmia/microphthalmia, is post-transcriptionally regulated by the conserved RNA-binding protein RBM24 in vertebrate eye development. Human Molecular Genetics; 29(4):591-604 View in: Pubmed
    *Featured on the cover
  8. Barnum C.E., Saai S.A., Patel S.D., Cheng C., Anand D., Xu X., Dash S., Siddam A.D., Glazewski L., Paglione E., Polson S., Chuma S., Mason R.W., Wei, S., Batish M., Fowler V.M., Lachke S.A. (2020) The Tudor-domain Protein TDRD7, Mutated in Congenital Cataract, Controls the Heat Shock Protein HSPB1 (HSP27) and Lens Fiber Cell Morphology. Human Molecular Genetics; 29(12):2076-2097. View in: Pubmed
    *Featured on the cover
  9. Dash S. †, Bhatt S. †, Sandell L. L., Seidel C., Ahn Y., Krumlauf R., Trainor P.A. (2020) The Mediator subunit, Med23 is required for embryonic survival and regulation of canonical WNT signaling during cranial ganglia development. Frontiers in Physiology; 11: 531933. View in: Pubmed
    † - Equal contribution
  10. Dash S., Bhatt S., Terrazas-Falcon K., Sandell L. L., Trainor P.A. (2021) Med23 Regulates Sox9 Expression during Craniofacial Development. Journal of Dental Research; 100(4):406-414. View in: Pubmed
  11. Terrazas-Falcon K. †, Watt K.E.N. †*, Dash S. †*, Zhao R., Sakai D., Moore E. L., Fitriasari S., Childers M., Sardiu M.E., Swanson S., Tsuchiya D., Unruh J., Bugarinovic G., Li L., Shiang R., Achilleos A., Dixon M.J., Dixon J., Trainor, P.A.* (2022) Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development. PNAS; 119(31):e2116974119. View in: Pubmed
    † - Equal contribution, * - co-corresponding author
  12. Dash S.*, Trainor P.A*. (2022) Nucleolin regulation of zebrafish craniofacial development. Development; 149(12):dev200349. View in: Pubmed
    * - co-corresponding author
  13. Dash S.#*, Lamb M.C.#, Lange, J.J., McKinney, M.C., Tsuchiya D., Guo F., Zhao X., Corbin T.J., Kirkman E., Delventhal K., Moore E.L., McKinney S., Shiang R., Trainor P.A.* (2023) rRNA transcription is integral to phase separation and maintenance of nucleolar structure. Accepted in PLOS Genetics (
    # - Equal contribution * - co-corresponding author

Review Papers

  1. Dash S., Siddam A.D., Barnum C.E., Janga S.C., Lachke S.A. (2016) RNA Binding Proteins in Eye Development and Disease: Implication of Conserved RNA Granule Components. WIREs RNA, 7(4):527-557. View in: Pubmed
    *Featured on the cover
  2. Dash S., Trainor P.A. (2020) The Development, Patterning and Evolution of Neural Crest Cell Differentiation Into Cartilage and Bone. Bone; 137:115409 View in: Pubmed