Dr. Fasullo’s research focuses on understanding cellular responses to toxins and radiation. Human susceptibility to environmental and industrial toxins is highly variable. Genetic factors that contribute to toxin sensitivity are difficult to determine by epidemiological studies. Dr. Fasullo’s research uses next generation sequencing for high- throuphput profiling of toxin resistance in model organisms to identify candidate human genes. He also uses budding yeast to characterize human cytochrome P450 polymorphisms that are associated with cancer susceptibility. He actively collaborates with researchers at University of California Berkeley and Northeastern University to develop new biosensors to rapidly characterize and identify chemical toxins.