Bijan K. Dey
My laboratory studies the function of non-coding RNAs, epigenetics and epitranscriptomics in skeletal muscle stem cell biology, cardiac muscle biology, muscle regeneration, and muscle degenerative diseases including Duchenne Muscular Dystrophy (DMD) and DMD-associated cardiomyopathy. DMD is a devastating X-linked childhood muscle degenerative disease. There is currently no effective treatment available that can either cure or stop the progression of DMD. The development of a successful therapy for DMD has been hindered due to the lack of a comprehensive understanding of the key myogenic processes and DMD pathophysiology at the cellular and molecular level. Our goal is to understand the fundamental molecular mechanism of muscle development and to devise new therapeutic and diagnostic platforms for DMD and related muscle degenerative diseases.