CFG core laboratories provide services to the research community on a fee-for-service basis. These services are available to investigators at the University at Albany, other academic institutions, and commercial entities.
Microarray and Next Gen Sequencing
The core provides Nextgen sequencing services on the Illumina Nextseq500 and Ion PGM platforms. Custom services for gene expression analysis using the Affymetrix GeneChip technology are also offered. Instrumentation for Agilent arrays and two-color experiments are also available.
DNA Sequencing & Fragment Analysis
The CFG utilizes Applied Biosystems' 3730XL DNA analyzer for sequencing and fragment analysis. CFG offers DNA sequencing services for a wide range of templates including plasmid DNA, PCR fragments, cosmid DNA, and bacterial genomic DNA.
Fragment analysis can be performed with the ABI DS33 dye set (6-FAM, VIC, NED, PET, and LIZ).
Quantitative PCR Services
The CFG utilizes Applied Biosystems' QuantStudio 12K Flex instrument to perform qPCR experiments. Available formats include 96 and 384 well plates, and Open Array.
Human Cell Line Authentication
The CFG DNA sequencing facility performs human cell line authentication by short tandem repeat (STR) profiling.
A wide range of custom services in molecular biology are available at the CFG. These include project-based services such as gene cloning and construction of insertion plasmids, Gateway cloning, gene discovery and characterization, gene expression studies, and recombinant protein expression and characterization.