SPH exterior

Vaccinology 101

Originally webcast June 16, 2011

Gary S. Marshall, MD
Professor of Pediatrics
Chief, Division of Pediatric Infectious Diseases, Director, Pediatric Clinical Trials Unit, University of Louisville School of Medicine

In order to effectively communicate the role of vaccination in preventative health, medical professionals must understand the science of vaccines.
This program will include a brief history of vaccinology and the fundamental immunological concepts that are necessary to understand how vaccines work: antibody and cytotoxic T cell responses, protein-polysaccharide conjugates, and adjuvants. It will also address the different types of vaccines, correlates of protection, herd immunity, and the goals of immunization programs.

Program Objectives:
After watching this broadcast participants will be able to:

  • Describe the function of antibodies and T cells in vaccine-induced protective immunity.
  • Identify the differences between responses to polysaccharide vaccines and protein-polysaccharide conjugate vaccines.
  • Classify vaccines into broad functional categories (live and inactivated) and identify the differences between them.
  • Describe the function of adjuvants.
  • Define the concepts of correlates of protection and herd immunity

This program was produced with funds provided through a cooperative agreement with CDC (Cooperative Agreement Number # 1U01IP000374).
It is offered through collaboration between the NurseTIP program and the Empire State PHTC.