E-Research Administration

Electronic Research for Multiple Agencies

Grants.Gov - serves as the Federal government's single interface for potential applicants/grantees to search and apply electronically for all Federal funding opportunities.
OSP Guidelines for Using Grants.gov

proposalCENTRAL - is an e-grantmaking website shared by many government, non-profit, and private grant-making organizations. Over twenty thousand applicants and reviewers interact electronically with the grant-makers that are members of proposalCENTRAL.

Federal Agencies

National Aeronautics and Space Administration (NSPIRES) - web-based system supports the entire lifecycle of NASA research solicitation and awards, from the release of solicitation announcements through the peer review and selection process, to awards management and publication of research results.

National Institutes of Health (NIH eRA Commons)

National Institutes of Health (Electronic Submission of Grant Applications)

National Science Foundation (FastLane)
Guidelines for Submitting NSF Applications

United States Department of Defense, Congressionally Directed Medical Research Programs - eReceipt Online Proposal Submission

United States Department of Education (e-Grants)

United States Department of Energy (e-Center)

Foundations

American Heart Association - electronic submission of your application is mandatory for all programs.  The application must be in pdf format.