The Center for Functional Genomics (CFG) maintains a comprehensive state-of-the-art research facility to support a wide range of services that are offered on a fee-per service basis to commercial and academic organizations.
We are able to coordinate efforts among our different Facilities so that we can accommodate researchers in projects from start to finish. For example, the CFG is able to isolate genes, design and make DNA constructs through our Molecular Biology Facility, then coordinate with the Mouse Transgenic Facility to make Transgenic or Knock-out mice and then the mice generated can be analyzed at the DNA, RNA or Protein levels through our Molecular Biology, Microarray, Laser Capture Microdissection or Proteomics Facilities.
The genomics services include a comprehensive range of custom services including gene cloning, gene discovery/characterization, gene expression and protein expression and characterization. We also offer standard oligonucleotide synthesis and DNA sequencing services using Applied Biosystems instrumentation and reagents.
Our proteomics core facility is well equipped for detailed studies on protein separation and characterization as well as related services including high-resolution 2D gel electrophoresis. We provide de-novo sequencing analysis of protein and peptides by mass spectrometry using a high sensitivity Q-tof mass spectrometer from Micromass/Waters.
The transgenics core laboratory offers a full range of services for the production of transgenic and targeted gene knockout mice including vector design and construction, microinjection and ES cell transfection. The mice produced at CFG are guaranteed to be Specific Pathogen Free (SPF).
Custom services for gene expression analysis using the Affymetrix GeneChip technology are currently offered at our microarray facility. Instrumentation for two-color experiments using custom made cDNA-based arrays is also available.
The LCM Facility at CFG has established various protocols for the analysis of tissue sections. We are able to collect pure cell populations from tissues that can be analyzed at the DNA, RNA or Protein levels.
We invite you to visit the web pages for the different services to obtain more detailed information about our offerings.