Shoup M**, Gallup AC**, Gallup G, McNay EC. Yawning Cools the Brain. Frontiers in Evolutionary Neuroscience (2010: in press) [link]
Paranjape SA***, Chan O, Zhu W, Horblitt AM, McNay EC, Cresswell JA, Bogan JS, McCrimmon RJ, Sherwin RS Influence of Insulin in the Ventromedial Hypothalamus on Pancreatic Glucagon Secretion In Vivo. Diabetes (2010) 59: 1521-27. [link]
McNay EC, Cotero VC***. Mini-review: Cognitive and Metabolic effects of recurrent hypoglycemia. Physiology & Behavior (2010) 100: 234-8 . [link]
McNay EC, Ong C*., McCrimmon RJ, Cressswell JA, Bogan JS, Sherwin RS. Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance. Neurobiology of Learning & Memory (2010) 93: 546-53. [link]
Fan X, Ding Y, Brown S, Zhou L, Shaw M, Vella MC, Cheng H, McNay EC, Sherwin RS, McCrimmon RJ. Hypothalamic AMP-activated Protein Kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of Type 1 diabetes. Am J Physiol Regul Integr Comp Physiol. (2009) 296: R1702-R1708. [link]
Page KA**, Williamson A, Yu N**, McNay EC, Dzuira J, McCrimmon RJ, Sherwin RS. Medium-chain fatty acids improve cognitive function in intensively treated type 1 diabetic patients and support in vitro synaptic transmission during acute hypoglycemia. Diabetes (2009) 58:1237-44. [link]
McCrimmon RJ, Shaw M, Fan X, Cheng H, Ding Y, Vella MC, Zhou L, McNay EC, Sherwin RS. Key Role for AMP-Activated Protein Kinase in the Ventromedial Hypothalamus in Regulating Counterregulatory Hormone Responses to Acute Hypoglycemia. Diabetes (2008), 57:444-450. [link]
Li H, Chen Y, Jones AF, Sanger RH, Collis LP, Flannery R, McNay EC, Yu T, Schwarzenbacher R, Bossy B, Bossy-Wetzel E, Bennett MV, Pypaert M, Hickman JA, Smith PJ, Hardwick JM, Jonas EA. BCL-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. PNAS (2008) 105(6): 2169-2174. [link]
Herzog RI***, Chan O***, Yu S, Dziura J, McNay EC, Sherwin RS. Effect of acute and recurrent hypoglycemia on brain glycogen concentration. Endocrinology (2008) 149(4):1499-1504. [link]
McNay EC. Insulin and ghrelin: peripheral hormones modulating memory and hippocampal function. Current Opinion in Pharmacology (2007) 7(6):628-32. [link]
McNay, E. C., Williamson, A. W., McCrimmon, R. J., & Sherwin, R. S. Cognitive and neural hippocampal effects of long-term, moderate recurrent hypoglycemia. Diabetes (2006), 55(4):1088-95. [link]
McCrimmon RJ, Song Z, Cheng H, McNay EC, Weikart-Yeckel C, Fan X, Routh VH, Sherwin RS. Corticotrophin releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia-induced hormonal counterregulation. Journal of Clinical Investigation (2006), 116(6):1723-30. [link]
McNay, E.C., Canal, C**. Sherwin, R. S. & Gold, P.E. Modulation of memory with septal injections of morphine and glucose: Effects on extracellular glucose levels in the hippocampus. Physiology & Behavior (2006), 87(2):298-303. [link]
Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, Horvath B, Gaskin FS, Nonaka N, Jaeger LB, Banks WA, Morley JE, Pinto S, Sherwin RS, Xu L, Yamada KA, Sleeman MW, Tschöp MH, Horvath TL. Ghrelin controls hippocampal spine synapse density and memory performance. Nature Neuroscience (2006), 9(3):381-8. [link]
McCrimmon, R.J., McNay, E. C. et al. Activation of AMP-Activated Protein Kinase Within the Ventromedial Hypothalamus Amplifies Counterregulatory Hormone Responses in Rats With Defective Counterregulation. Diabetes (2006), 55(6):1755-60. [link]
McNay, E. C. The impact of recurrent hypoglycemia on cognitive function in aging. Neurobiology of Aging (2005), 26: S76-S79. [link]
McCrimmon RJ, Evans ML, Fan X, McNay EC, Chan O, Ding Y, Zhu W, Gram DX, Sherwin RS. Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats. Diabetes (2005), 54(11):3169-74. [link]
Canal, C.**, McNay, E.C., & Gold, P.E. Increases in extracellular fluid glucose levels in the rat hippocampus following an anesthetic dose of pentobarbital or ketamine-xylazine: an in vivo microdialysis study. Physiology & Behavior (2005), 84: 245-250. [link]
Evans ML, McCrimmon RJ, Flanagan DE, Keshavarz T, Fan X, McNay EC, Jacob RJ, Sherwin RS. Hypothalamic ATP-sensitive K + Channels Play a Key Role in Sensing Hypoglycemia and Triggering Counterregulatory Epinephrine and Glucagon Responses. Diabetes (2004), 53: 2542-2551. [link]
McNay, E. C. & Sherwin, R. S. From aCSF to aECF: Microdialysis perfusate composition effects on in vivo brain ECF glucose measurements. Journal of Neuroscience Methods (2004), 132(1):35-43. [link]
McNay, E.C. & Sherwin, R. S. Effect of recurrent hypoglycemia on spatial cognition and cognitive metabolism in normal and diabetic rats. Diabetes (2004), 53(2):418-25. [link]
McNay, E.C. & Brown, T. H. Preponderance of late-spiking neurons in lateral amygdala. Cogprints (2003), online: http://cogprints.ecs.soton.ac.uk/archive/00003067/ [link]
McCrimmon, R. J. Jacob, R. J., Fan, X., McNay, E. C. & Sherwin R. S. Effects of recurrent antecedent hypoglycaemia and chronic hyperglycaemia on brainstem extra-cellular glucose concentrations during acute hypoglycaemia in conscious diabetic BB rats. Diabetologia (2003). 46(12):1658-61. [link]
McNay, E. C. & Gold, P. E. Food for thought: fluctuations in brain extracellular glucose provide insight into the mechanisms of memory modulation. Cognitive and Behavioral Neuroscience Reviews (2002), 1: 264-280. [link]
Moyer, J. R. Jr., McNay, E. C., & Brown, T. H. Three classes of pyramidal neurons in layer V of rat perirhinal cortex. Hippocampus (2002), 12: 218-234. [link]
McNay, E. C. & Gold, P. E. Age-related differences in hippocampal extracellular fluid glucose concentration during behavioral testing and following systemic glucose administration. Journal of Gerontology (2001), 56: B66-B71. [link]
McNay, E. C., McCarty, R. C. & Gold, P. E. Fluctuations in brain glucose concentration during behavioral testing: dissociations between brain areas and between brain and blood. Neurobiology of Learning and Memory (2001), 75: 325-337. [link]
McNay, E. C., Fries, T. M.* & Gold, P. E. Decreases in rat extracellular hippocampal glucose concentration associated with cognitive demand during a spatial task. Proceedings of the National Academy of Sciences (2000), 97: 2881-2885.
Reported in AP wire article and subsequently widely, including reports on the BBC, CNN, New York Times and translations into several languages. [link]
McNay, E. C. & Gold, P. E. Extracellular glucose concentrations in the brain - a response. Journal of Neurochemistry (1999), 73, 2222-2223. [link]
McNay, E. C. & Gold, P. E. Extracellular glucose concentrations in the rat hippocampus measured by zero-net-flux: Effects of microdialysis flow rate, strain and age. Journal of Neurochemistry (1999), 72: 785-790. [link]
McNay, E. C. & Gold, P. E. Memory modulation across neural systems: Intra-amygdala glucose reverses deficits caused by intra-septal morphine on a spatial task, but not on an aversive task. Journal of Neuroscience (1998), 18: 3853-3858. [link]
McNay, E. C. & Willingham, D. B. Deficit in strategic motor skill learning, but not perceptuomotor recalibration, with aging. Learning and Memory (1998), 4: 411-420. [link]