Sequeira SJ, Ranganathan AC, Adam AP, Iglesias BV, Farias EF, Aguirre-Ghiso JA.
Inhibition of Proliferation by PERK Regulates Mammary Acinar Morphogenesis and Tumor Formation.
PLoS ONE. 2007 Jul 18; 2:e615. PMID: 17637831 [PubMed - in process]
Shinohara M, Mikhailov AV, Aguirre-Ghiso JA, Rieder CL.
ERK1/2 Activity Is Not Required in Mammalian Cells during Late G2 for Timely Entry into or Exit from Mitosis.
Mol Biol Cell. 2006 Oct 11; [Epub ahead of print] PMID: 17035635 [PubMed - as supplied by publisher]
Aguirre-Ghiso JA.
The problem of cancer dormancy: understanding the basic mechanisms and identifying therapeutic opportunities.
Cell Cycle. 2006 Aug;5(16):1740-3. Epub 2006 Aug 15.
PMID: 16929164 [PubMed - in process]
Ranganathan AC, Adam AP, Aguirre-Ghiso JA.
Opposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancy.
Cell Cycle. 2006 Aug;5(16):1799-807. Epub 2006 Aug 15.
PMID: 16929185 [PubMed - in process]
Ranganathan AC, Adam AP, Zhang L, Aguirre-Ghiso JA.
Tumor Cell Dormancy Induced by p38(SAPK) and ER-Stress Signaling: An Adaptive Advantage for Metastatic Cells?
Cancer Biol Ther. 2006 Jul 1;5(7) [Epub ahead of print], PMID: 16861922 [PubMed - as supplied by publisher]
Chaurasia P, Aguirre-Ghiso JA, Liang OD, Gardsvoll H, Ploug M, Ossowski L.
A region in uPAR domain III controlling a functional association with alpha 5beta 1-integrin and tumor growth.
J Biol Chem. 2006 Mar 17; [Epub ahead of print]
Ranganathan AC, Zhang L, Adam AP, and Julio Aguirre Ghiso.
Functional coupling of p38-induced upregulation of BiP and activation of PERK to drug resistance of dormant carcinoma cells.
Cancer Res. 2006 Feb 1;66(3):1702-11
Tenenbaum SA and Julio A. Aguirre-Ghiso.
Dephosphorylation Shows SR Proteins the Way Out.
Molecular Cell (2005); 20 (4); 499-501
Timothy E. Baroni, Michele T. Lastro, Aparna C. Ranganathan, Scott A. Tenenbaum,
Douglas S. Conklin, and Julio A. Aguirre-Ghiso.
Ribonomic and Short Hairpin RNA Gene Silencing Methods to Explore Functional Gene Programs Associated with Tumor Growth Arrest.
Cancer Genomics and Proteomics. Methods Protocols. Methods in Molecular Biology, Humana Press. In Press. 2005
Kip M. Connor, Sita Subbaram, Kevin J. Regan, Kristin K. Nelson,
Joseph E. Mazurkiewicz , Peter J. Bartholomew, Andrew E. Aplin, Yu-Tzu Tai ,
Julio Aguirre-Ghiso, Sonia C. Flores and J. Andres Melendez.
Mitochondrial H2O2 Regulates the Angiogenic Phenotype Via PTEN Oxidation.
J. Biol. Chem. (2005) Feb 8; [Epub ahead of print]
Julio A. Aguirre-Ghiso, Liliana Ossowski and Sarah K. Rosenbaum.
GFP tagging of ERK and p38 pathways reveals novel dynamics of pathway activation during primary and metastatic growth.
Cancer Res (2004); 64(20):7336-45
Faculty of 1000 evaluation at: http://www.f1000biology.com/article/15492254/evaluation
Mazzoni E, Adam A, Bal de Kier Joffe E, Aguirre-Ghiso JA.
Immortalized mammary epithelial cells overexpressing protein kinase C gamma acquire a malignant phenotype and become tumorigenic in vivo.
Mol Cancer Res. 2003 Aug;1(10):776-87
Aguirre-Ghiso JA, Estrada Y, Liu D, Ossowski L.
ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK).
Cancer Res. 2003 Apr 1;63(7):1684-95
Liu D, Aguirre Ghiso J, Estrada Y, Ossowski L.
EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma.
Cancer Cell. 2002 Jun;1(5):445-57
Faculty of 1000 Evaluation at: http://www.f1000biology.com/article/12124174/evaluation
Aguirre Ghiso JA.
Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo.
Oncogene. 2002 Apr 11;21(16):2513-24
Aguirre-Ghiso JA, Liu D, Mignatti A, Kovalski K, Ossowski L.
Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo.
Mol Biol Cell. 2001 Apr;12(4):863-79
Ossowski L, Aguirre-Ghiso JA.
Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.
Curr Opin Cell Biol. 2000 Oct;12(5):613-20. Review
Aguirre Ghiso JA, Kovalski K, Ossowski L.
Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling.
J Cell Biol. 1999 Oct 4;147(1):89-104
Aguirre Ghiso JA, Alonso DF, Farias EF, Gomez DE, de Kier Joffe EB.
Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype.
Eur J Biochem. 1999 Jul;263(2):295-304. Review
