Lauren Endres

Lauren Endres

Assistant Professor of Biology, SUNY Polytechnic Institute
RNA Institute
Lauren Endres
About

The broad goal of my research program is to understand translational defense mechanisms that protect against oxidative-stress, with implications for the prevention of cancer and its progression from a benign to a malignant state. Specifically, I am investigating tRNA methyltransferases that are reactive oxygen species responsive and that show deregulated expression in a number of cancers, including colon, bladder, breast and ovarian. I aim understand the interrelationships between these fascinating enzymes, the modifications they catalyze, and known oncogenic and tumor suppressor signaling pathways.