No cell lives in isolation. Instead, cells constantly communicate with each other and their environment via cell-to-cell signaling.

• Our lab studies cells cell-to-cell signaling pathways, to understand how they regulate animal development.

• Our current research focus is Notch signaling and its regulation of transcription (activation, dynamics) in the germline stem cells.

• We use a multidisciplinary approach, combining biochemistry, genetics, molecular&cell biology, quantitative imaging, computational biology and statistics.

• We use the nematode C. elegans as a model system, which allow us to analyze the cell signaling response in its native context at a single-molecule level.