Douglas Conklin


  • Douglas Conklin

    BIOMEDICAL SCIENCES

    Dr. Conklin’s laboratory uses RNAi-based functional genomic approaches to study mechanisms of human cancer cell proliferation and survival. These studies stem from previous work on the initial development of shRNAs and shRNA libraries for mammalian gene function analysis. High-throughput gene function studies have been performed to identify new genes critical to the survival of human cancer cells. Hypothesis-driven analyses of genes identified in these studies continue. The goal of the work is to develop RNAi or small molecule therapeutics as cancer therapeutics. The laboratory has been federally funded for several years to continue these approaches on breast cancer.