University at Albany
 

Physics Faculty

Carolyn MacDonald
Professor, Director X-Ray Institute

Office: Physics 216 / ES B14
Telephone: (518) 442-4504 / 591-8869
Email: c.macdonald@albany.edu

Academic History:
  • Ph.D. Harvard University (1986)
  • Assisstant Professor, University at Albany (1986-1994)
  • Associate Director, Center for X-ray Optics (1991-2002) 
  • Associate Professor, University at Albany (1994-1998)
  • Professor, University at Albany (1998-present)
  • Director, Center for X-ray Optics (2002-present)
  • Chair, Physics (2008-present)
Research Areas:
  • Medical imaging 
  • Materials science 
  • X-ray Optics 
Current Research:
My current research is primarily involved with the development of x-ray technology, especially the application of crystal and polycapillary x-ray optics to a variety of applications, including medical imaging, therapy, and materials analysis. Areas of current investigation include the use of scatter rejection grids to tissue type imaging, the use of polycapillary and curved crystal optics to produce monochromatic beams for diffraction enhanced and phase imaging, the development of a "micro gamma camera" for scintography, and the development of convergent beam diffraction systems for protein and  macromolecular crystallography.
Research Links:
http://www.albany.edu/x-ray-optics
Recent Publications:

M. Bass, C. DeCusatis, J Enoch, V. Lakshminarayanan, G. Li, C. MacDonald, V.N. Mahajan, E. Van Stryland, eds., Handbook of Optics Third Ed., Volumes I-V, McGraw-Hill 2010.

C.A. MacDonald, Focusing Polycapillary Optics and their Applications, X-Ray Optics and Instrumentation, special issue X-Ray Focusing: Techniques and Applications, Volume 2010 (2010), Article ID 867049, 17 pages, doi:10.1155/2010/867049.

Wei Zhou, Dip Mahato, C.A. MacDonald, “Analysis of Powder X-Ray Diffraction Resolution Using Collimating and Focusing Polycapillary Optics,” Thin Solid Films 518 (18) July 2010, pp. 5047-5056.

C. A. MacDonald and W.M. Gibson, Polycapillary Optics, in Handbook of Optics, Third Edition Volume V: Atmospheric Optics, Modulators, Fiber Optics, X-Ray and Neutron Optics.

S.M. Lee and C.A. MacDonald, X-ray Tube Sources, in Handbook of Optics, Third Edition Volume V: Atmospheric Optics, Modulators, Fiber Optics, X-Ray and Neutron Optics.

Robert Schmitz and C.A. MacDonald “Modeling Complex Optical Systems”, in Advances in X-Ray/EUV Optics and Components V, S. Goto, A. M. Khounsary, C. Morawe, eds., SPIE vol. 7802, 2010.

Dip N. Mahato and C. A. MacDonald, “Potential for focused beam orthovoltage therapy,” Penetrating Radiation Systems and Applications XI,  F. P. Doty, H. B. Barber, H. Roehrig, R. C. Schirato, SPIE vol. 7806, 2010.

Ayhan Bingolbali and C.A. MacDonald, "Curved crystal x-ray optics for monochromatic imaging with a clinical source,” Med. Phys. Volume 36, Issue 4, pp. 1176-1183, 2009.

N. Mail, C. MacDonald and W. M. Gibson, “Microscintigraphy with high resolution collimators and radiographic imaging detectors” Medical Physics 36 (2), pp. 645-655, 2009.

Ayhan Bingolbali and C. A. MacDonald, “Quality assessment system for curved crystal X-ray optics," Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Volume 267, Issue 5, March 2009, Pages 832-841.

C.A. MacDonald, S.M. Owens, and W.M. Gibson, "Polycapillary X-Ray  Optics for Microdiffraction," Journal of Applied Crystallography, 32, pp160-7, 1999 

S.M. Jorgensen, D.A. Reyes, C.A. MacDonald, E.L. Ritman, "Micro-CT  Scanner With A Focusing Polycapillary X-Ray Optic,"in U. Bonse, ed.,  Developments in X-Ray Tomography II, SPIE vol. 3772, 1999, 
pp. 158-166. 

C.H. Russell, M. Gubarev, J. Kolodziejczak, M. Joy, C.A. MacDonald,  and W.M. Gibson, "Polycapillary X-ray Optics for X-ray Astronomy," in  Advances in X-ray Analysis, 43, Proceedings of the 48th Denver X-ray Conference, 1999. 

W.M. Gibson and C.A. MacDonald, section editors, "X-ray and Neutron  Optics," Handbook of Optics, Vol. III, McGraw-Hill 2000. 
C.A. MacDonald and S.D. Padiyar, "How Photons Work," cover article, Photonics Spectra, August 2000. 

C.A. MacDonald, Ali M. Khounsary, eds., Advances in Laboratory-Based  X-Ray Sources and Optics, SPIE vol. 4144, 2000. 

F.A. Hofmann, W.M. Gibson, C.A. MacDonald, D.A. Carter, J.X. Ho,  J.R. Ruble, "Polycapillary Optic - Source combinations for Protein  Crystallography," Jour. Applied Crys. 34, pp.330-335, 2001. 

Francisca Sugiro and C.A. MacDonald, "Monochromatic Imaging with a  Conventional Source Using Polycapillary X-ray Optics," in  L.E. Antonuk, M.J. Yaffe, eds., Medical Imaging 2001:Physics of  Medical Imaging, SPIE vol. 4320, pp. 427-434, 2001. 

Ali M. Khounsary , C.A. MacDonald, eds., Advances in Laboratory-Based X-Ray Sources and Optics II, SPIE vol. 4502, 2001. 

C.A. MacDonald, W.M. Gibson, and W. Peppler, "X-Ray Optics for Better  Diagnostic Imaging," Technology In Cancer Research And Treatment, 1,  (2), April 2002, pp 111-118. 

Ali M. Khounsary , C.A. MacDonald, eds., Advances in Laboratory-Based X-Ray Sources and Optics III, SPIE vol. 4781, to be published 2002. 
W. M. Gibson, C.A. MacDonald, and N. Mail, "Potential for Radioscintography with Polycapillary Optics," in Ali M. Khounsary ,  C.A. MacDonald, eds., Advances in Laboratory-Based X-Ray Sources and  Optics III, SPIE vol. 4781, pp. 104-111, 2002.

M. Bass, C. DeCusatis, J Enoch, V. Lakshminarayanan, G. Li, C. MacDonald, V.N. Mahajan, E. Van Stryland, Handbook of Optics Third Ed., Volumes I-V, to be published McGraw-Hill 2009.

G.A. Kyrala, J-C J. Gauthier, C.A. MacDonald, A.M. Khounsary, eds., Laser-Generated, Synchrotron, and Other Laboratory X-ray and EUV Sources, Optics, and Applications II, SPIE vol. 5918, 2005.

C.A. MacDonald, A.T. Macrander, T. Ishikawa,C. Morawe, J.L. Wood, eds., X-ray Sources and Optics, SPIE vol. 5537, 2004.

George A. Kyrala, Jean-Claude J. Gauthier, Carolyn A. MacDonald, Ali M. Khounsary, eds., Laser-Generated and Other Laboratory X-Ray and EUV Sources, Optics, and Applications, SPIE vol. 5196, 2003.

C. A. MacDonald, An Introduction to X-ray and Neutron Optics, in Handbook of Optics, Third Edition Volume V: Atmospheric Optics, Modulators, Fiber Optics, X-Ray and Neutron Optics, to be published McGraw-Hill 2009.

C. A. MacDonald and W.M. Gibson, Polycapillary Optics, in Handbook of Optics, Third Edition Volume V: Atmospheric Optics, Modulators, Fiber Optics, X-Ray and Neutron Optics, to be published McGraw-Hill 2009.

S.M. Lee and C.A. MacDonald, X-ray Tube Sources, in Handbook of Optics, Third Edition Volume V: Atmospheric Optics, Modulators, Fiber Optics, X-Ray and Neutron Optics, to be published McGraw-Hill 2009.

Ayhan Bingolbali and C.A. MacDonald, "Curved crystal x-ray optics for monochromatic imaging with a clinical source,” Med. Phys. Volume 36, Issue 4, pp. 1176-1183, 2009.

Wei Zhou and C.A. MacDonald, “Analysis of Powder Diffraction with Polycapillary Optics,” accepted, Thin Solid Films.

N. Mail, C. MacDonald and W. M. Gibson, “Microscintigraphy with high resolution collimators and radiographic imaging detectors” Medical Physics 36 (2), pp. 645-655, 2009.

Ayhan Bingolbali and C. A. MacDonald, " Quality assessment system for curved crystal X-ray optics," Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Volume 267, Issue 5, March 2009, Pages 832-841.

Z. W. Chen, W. M. Gibson, N. Mail, C. A. MacDonald, “Total reflection x-ray fluorescence with low power sources coupled to doubly curved crystal optics,” Spectrochimica. Acta. B, 60 (4), pp.471-8, 2005.

F.R. Sugiro, Danhong Li,  C.A. MacDonald, “Beam Collimation with Polycapillary X-ray Optics for High Contrast High Resolution Monochromatic Imaging,”, Med. Phys., 31, p. 3288, 2004.

C.A. MacDonald and W.M. Gibson,  “Applications and Advances In Polycapillary Optics”,  X-ray Spectrometry, 32 (3), 2003, pp 258-268.

Ayhan Bingölbali, Wei Zhou, Dip N. Mahato and C.A. MacDonald, "Focused beam powder diffraction with polycapillary and curved crystal optics," inAdvances in X-Ray/EUV Optics and Components IIIProceedings of SPIE Volume 7077,  A.M. Khounsary, C. Morawe, S. Goto, eds.,  2008.

Wei Zhou and C.A. MacDonald, Diffraction Imaging with Conventional Sources, in Advances in X-Ray/EUV Optics and Components III, Proceedings of SPIE Volume 7077,  A.M. Khounsary, C. Morawe, S. Goto, eds.,  2008.

Robert Schmitz, Ayhan Bingölbali, Abrar Hussain and C. A. MacDonald, "Development of Polarized and Monochromatic X-Ray Beams From Tube Sources in Advances," in X-Ray/EUV Optics and Components III, Proceedings of SPIE Volume 7077,  A.M. Khounsary, C. Morawe, S. Goto, eds., 2008.

C.A. MacDonald, Noor Mail, W.M. Gibson, SM Jorgensen, E L Ritman, “Micro gamma camera optics with high sensitivity and resolution”, invited in M. J. Flynn, ed., Physics of Medical Imaging, SPIE vol. 5745, pp.1-6, 2005.

Danhong Li, Noor Mail, C.A. MacDonald, “A comparison of doubly curved crystal and polycapillary optics for monochromatic beam production from a clinical source,” in M. J. Flynn, ed., Physics of Medical Imaging, SPIE vol. 5745, pp.754-763, 2005.

N. Mail, Z. W. Chen, W. M. Gibson, C. A. MacDonald, “Application of Doubly-Curved Crystal Optics,” in X-ray Sources and Optics, C.A. MacDonald, A.T. Macrander, T. Ishikawa,C. Morawe, J.L. Wood, eds., SPIE vol. 5537, pp. 94-104, 2004.

D. Li, F.R. Sugiro, C.A. MacDonald, “Source-optic optimization for compact monochromatic imaging”, in X-ray Sources and Optics, C.A. MacDonald, A.T. Macrander, T. Ishikawa,C. Morawe, J.L. Wood, eds., SPIE vol. 5537, pp. 105-114, 2004.

Jorgensen SM, Chmelik MS, Eaker DR, MacDonald CA, Ritman E L A “Polycapillary X-ray Optics-based Integrated micro-SPECT/CT Scanner,” inDevelopments in X-ray Tomography IV, Ulrich Bonse, ed., SPIE vol. 5535, pp 36-42, 2004.

C.A. MacDonald, N. Mail, D. Li, M. Roy, and F. Sugiro, “Monochromatic Applications of Polycapillary Optics”, in Laser-Generated and Other Laboratory X-Ray and EUV Sources, Optics, and Applications, George A. Kyrala, Jean-Claude J. Gauthier, Carolyn A. MacDonald, Ali M. Khounsary, eds., SPIE vol. 5196, pp. 405-411, 2003.

Patents:

X-ray Imaging System Employing Point-Focusing, Curved Monochromatic Optics, patent number 07583789, disclosed 2005, filed 2006, granted 2009.

Wide field coherent scatter imaging for radiography using a divergent beam, disclosed 5/2003, application 0794.075filed 12/2006, revised 1/2007, 2/2009, 8/2009, allowed 10/2009.