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Department of Biological Sciences
 

Faculty
Hua Shi

Publications
 
  • Sevilimedu, A., Shi, H., and Lis, J.T. (2008) TFIIB aptamers inhibit
    transcription by perturbing PIC formation at distinct stages. Nucleic Acids
    Research, 36, 3118-3127.
  • Huang, Z., Pei, W.M., Jayaseelan, Shi, H., and Niu, L. (2007) RNA aptamers selected against the GluR2 AMPA receptor channels expressed in HEK-293 cells. Biochemistry, 46, 12648-12655.
  • Shi, H. [co-corresponding author], Fan, X., Sevilimedu, A., and Lis, J.T. (2007) RNA aptamers directed to discrete functional sites on a single protein structural domain. Proc. Natl. Acad. Sci. USA, 104, 3742-3746.
  • Zhao, X., Shi, H., Sevilimedu,A., Liachko, N., Nelson, H., and Lis, J.T. (2006) An RNA aptamer that interferes with the DNA binding of the HSF transcription activator. Nucleic Acids Research, 34, 3763-3769.
  • Fan, X., Shi, H., and Lis, J. T. (2005) Distinct transcriptional responses of RNA polymerases I, II, and III to aptamers that bind TBP. Nucleic Acids Research, 33, 838-845.
  • Fan, X., Shi, H. [co-first author], Adelman, K., and Lis, J. T. (2004) Probing TBP interactions in transcription initiation and reinitiation with RNA aptamers that act in distinct modes. Proc. Natl. Acad. Sci. USA, 101, 6934-6939.
  • Kim, S., Shi, H., Lee, D-k., and Lis, J. T. (2003) Specific SR protein-dependent splicing substrates identified through genomic SELEX. Nucleic Acids Research, 31, 1955-1961.
  • Shi, H. [co-corresponding author], Fan, X., Ni, Z., and Lis, J. T. (2002) Evolutionary dynamics and population control during in vitro selection and amplification with multiple targets. RNA, 8, 1461-1470.
  • Shi, H., Hoffman, B. E., and Lis, J. T. (1999) RNA aptamers as effective protein antagonists in a multicellular organism. Proc. Natl. Acad. Sci. USA, 96, 10033-10038.
  • Ulrich, H., et al (1998) In vitro selection of RNA molecules that displace cocaine from the membrane-bound nicotinic acetylcholine receptor. Proc. Natl. Acad. Sci. USA, 95, 14051-14056.
  • Shi, H., Ziegelbauer, J. M., Hoffman, B. E., and Lis, J. T. (1997) Artificial genes expressing RNA aptamers as specific protein inhibitors in vivo. Nucleic Acids Symposium Series, No. 36, 194-196.
  • Shi, H., Hoffman, B. E., and Lis, J. T. (1997) A specific RNA hairpin loop structure binds the RNA recognition motifs of the Drosophila SR protein B52. Molecular and Cellular Biology, 17(5), 2649-2657.

 

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