Chapter 8

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electromyogram/EMG

An electrical potential recorded from an electrode placed on or in a muscle.

electro-oculogram/EOG

An electrical potential from the eyes, recorded by means of electrodes placed on the skin around them; detects eye movements.

alpha activity

Smooth electrical activity of 8-12 Hz recorded from the brain; generally associated with a state of relaxation.

beta activity

Irregular electrical activity of 13-30 Hz recorded from the brain; generally associated with a state of arousal.

synchrony

High-voltage, low-frequency EEG activity, characteristic of slow-wave sleep or coma, during which neurons fire together in a regular fashion.

desynchrony

Irregular electrical activity recorded from the brain, generally associated with periods of arousal.

theta activity

EEG activity of 5-8 Hz that occurs intermittently during early stages of slow-wave sleep and REM sleep.

delta activity

Regular, synchronous electrical activity of approximately 1-4 Hz recorded from the brain; occurs during the deepest stages of slow-wave sleep.

REM sleep

A period of desynchronized EEG activity during sleep, at which time dreaming, rapid eye movements, and muscular paralysis occur; also called paradoxical sleep.

non-REM sleep

All stages of sleep except REM sleep.

slow-wave sleep

Non-REM sleep, characterized by synchronized EEG activity during its deeper stages.

basic rest-activity cycle/BRAC

A 90-min cycle (in humans) of waxing and waning alertness, controlled by a biological clock in the caudal brain stem; controls cycles of REM sleep and slow-wave sleep.

fatal familial insomnia

A fatal inherited disorder characterized by progressive insomnia.

rebound phenomenon

The increased frequency or intensity of a phenomenon after it has been temporarily suppressed; for example, the increase in REM sleep seen after a period of REM sleep deprivation.

locus coeruleus

A dark-colored group of noradrenergic cell bodies located in the pons near the rostral end of the floor of the fourth ventricle; involved in arousal and vigilance.

raphe nuclei

A group of nuclei located in the reticular formation of the medulla, pons, and midbrain, situated along the midline; contain serotonergic neurons.

basal forebrain region

The region at the base of the forebrain rostral to the hypothalamus; involved in thermoregulation and control of sleep.

POAH

The region of the preoptic area and the adjacent anterior hypothalamus, involved in thermoregulation and induction of slow-wave sleep.

PGO wave

Bursts of phasic electrical activity originating in the pons, followed by activity in the lateral geniculate nucleus and visual cortex; a characteristic of REM sleep.

peribrachial area

The region around the brachium conjunctivum, located in the dorsolateral pons; contains acetylcholinergic neurons involved in the initiation of REM sleep.

carbachol

A drug that stimulates acetylcholine receptors.

medial pontine reticular formation/MPRF

A region that contains neurons involved in the initiation of REM sleep; activated by acetylcholinergic neurons of the peribrachial area.

magnocellular nucleus

A nucleus in the medulla; involved in the atonia (muscular paralysis) that accompanies REM sleep.

drug dependency insomnia

An insomnia caused by the side effects of ever-increasing doses of sleeping medications.

sleep apnea

Cessation of breathing while sleeping.

narcolepsy

A sleep disorder characterized by periods of irresistible sleep, attacks of cataplexy, sleep paralysis, and hypnagogic hallucinations.

sleep attack

A symptom of narcolepsy; an irresistible urge to sleep during the day, after which the person awakes feeling refreshed.

cataplexy

A symptom of narcolepsy; complete paralysis that occurs during waking.

sleep paralysis

A symptom of narcolepsy; paralysis occurring just before a person falls asleep.

hypnagogic hallucination

A symptom of narcolepsy; vivid dreams that occur just before a person falls asleep; accompanied by sleep paralysis.

REM without atonia

A neurological disorder in which the person does not become paralyzed during REM sleep and thus acts out dreams.

circadian rhythm

A daily rhythmical change in behavior or physiological process.

zeitgeber

A stimulus (usually the light of dawn) that resets the biological clock responsible for circadian rhythms.

suprachiasmatic nucleus/SCN

A nucleus situated atop the optic chiasm. It contains a biological clock responsible for organizing many of the body's circadian rhythms.

intergeniculate leaflet/IGL

A part of the lateral geniculate nucleus that receives information from the retina and projects to the SCN.

neuropeptide Y

A peptide released by the terminals of the neurons that project from the IGL to the SCN.

pineal gland

A gland attached to the dorsal tectum; produces melatonin and plays a role in circadian and seasonal rhythms.

melatonin

A hormone secreted during the night by the pineal body; plays a role in circadian and seasonal rhythms.

Chapter 10

52

sexually dimorphic behavior

A behavior that has different forms or that occurs with different probabilities or under different circumstances in males and females.

gamete

A mature reproductive cell; a sperm or ovum.

sex chromosome

The X and Y chromosomes, which determine an organism's gender. Normally, XX individuals are female, and XY individuals are male.

gonad

An ovary or testis.

organizational effect

The effect of a hormone on tissue differentiation and development.

activational effect

The effect of a hormone that occurs in the fully developed organism; may depend on the organism's prior exposure to the organizational effects of hormones.

Müllerian system/Mullerian system

The embryonic precursors of the female internal sex organs.

Wolffian system

The embryonic precursors of the male internal sex organs.

anti-Müllerian hormone/anti-Mullerian hormone

A peptide secreted by the fetal testes that inhibits the development of the Müllerian system, which would otherwise become the female internal sex organs.

defeminizing effect

An effect of a hormone present early in development that reduces or prevents the later development of anatomical or behavioral characteristics typical of females.

androgen

A male sex steroid hormone. Testosterone is the principal mammalian androgen.

masculinizing effect

An effect of a hormone present early in development that promotes the later development of anatomical or behavioral characteristics typical of males.

testosterone

The principal androgen found in males.

dihydrotestosterone

An androgen, produced from testosterone through the action of the enzyme 5à" reductase.

androgen insensitivity syndrome

A condition caused by a congenital lack of functioning androgen receptors; in a person with XY sex chromosomes, causes the development of a female with testes but no internal sex organs.

persistent Müllerian duct syndrome/persistent Mullerian duct syndrome

A condition caused by a congenital lack of functioning anti-Müllerian hormone receptors; in a male, causes development of both male and female internal sex organs.

Turner's syndrome

The presence of only one sex chromosome (an X chromosome); characterized by lack of ovaries but otherwise normal female sex organs and genitalia.

gonadotropin releasing hormone

A hypothalamic hormone that stimulates the anterior pituitary gland to secrete gonadotropic hormone.

gonadotropic hormone

A hormone of the anterior pituitary gland that has a stimulating effect on cells of the gonads.

follicle-stimulating hormone/FSH

The hormone of the anterior pituitary gland that causes development of an ovarian follicle and the maturation of its oocyte into an ovum.

luteinizing hormone/LH

A hormone of the anterior pituitary gland that causes ovulation and development of the ovarian follicle into a corpus luteum.

estradiol

The principal estrogen of many mammals, including humans.

estrogen

A class of sex hormones that cause maturation of the female genitalia, growth of breast tissue, and development of other physical features characteristic of females.

menstrual cycle

The female reproductive cycle of most primates, including humans; characterized by growth of the lining of the uterus, ovulation, development of a corpus luteum, and (if pregnancy does not occur), menstruation.

estrous cycle

The female reproductive cycle of mammals other than primates.

ovarian follicle

A cluster of epithelial cells surrounding an oocyte, which develops into an ovum.

corpus luteum

A cluster of cells that develops from the ovarian follicle after ovulation; secretes estradiol and progesterone.

progesterone

A steroid hormone produced by the ovary that maintains the endometrial lining of the uterus during the later part of the menstrual cycle and during pregnancy; along with estradiol, it promotes receptivity in female mammals with estrous cycles.

refractory period

A period of time after a particular action (for example, an ejaculation by a male) during which that action cannot occur again.

Coolidge effect

The restorative effect of introducing a new female sex partner to a male that has apparently become "exhausted" by sexual activity.

aromatization

A chemical reaction catalyzed by an aromatase; the process by which testosterone is transformed into estradiol.

oxytocin

A hormone secreted by the posterior pituitary gland; causes contraction of the smooth muscle of the milk ducts, the uterus, and the male ejaculatory system; also serves as a neurotransmitter in the brain.

prolactin

A hormone of the anterior pituitary gland, necessary for production of milk; has an inhibitory effect on male sexual behavior.

lordosis

A spinal sexual reflex seen in many four-legged female mammals; arching of the back in response to approach of a male or to touching the flanks, which elevates the hindquarters.

pheromone

A chemical released by one animal that affects the behavior or physiology of another animal; usually smelled or tasted.

Lee-Boot effect

The increased incidence of false pregnancies seen in female animals that are housed together; caused by a pheromone in the animals' urine; first observed in mice.

Whitten effect

The synchronization of the menstrual or estrous cycles of a group of females, which occurs only in the presence of a pheromone in a male's urine.

Vandenbergh effect

The earlier onset of puberty seen in female animals that are housed with males; caused by a pheromone in the male's urine; first observed in mice.

Bruce effect

Termination of pregnancy caused by the odor of a pheromone in the urine of a male other than the one that impregnated the female; first identified in mice.

vomeronasal organ

A sensory organ that detects the presence of certain chemicals, especially when a liquid is actively sniffed; mediates the effects of some pheromones.

accessory olfactory bulb

A neural structure located in the main olfactory bulb that receives information from the vomeronasal organ.

medial nucleus of the amygdala

A nucleus that receives olfactory information from the olfactory bulb and accessory olfactory bulb; involved in the effects of odors and pheromones on reproductive behavior.

congenital adrenal hyperplasia/CAH

A condition characterized by hypersecretion of androgens by the adrenal cortex; in females, causes masculinization of the external genitalia.

spinal nucleus of the bulbocavernosus/SNB

A nucleus located in the lower spinal cord; in some species of rodents, present only in males.

medial preoptic area/MPA

An area of cell bodies just rostral to the hypothalamus; plays an essential role in male sexual behavior.

sexually dimorphic nucleus

A nucleus in the preoptic area that is much larger in males than in females; first observed in rats; plays a role in male sexual behavior.

vasopressin

A hormone secreted by the posterior pituitary gland that controls the secretion of urine by the kidneys; also serves as a neurotransmitter in the brain.

ventromedial nucleus of the hypothalamus/VMH

A large nucleus of the hypothalamus located near the walls of the third ventricle; plays an essential role in female sexual behavior.

periaqueductal gray matter/PAG

The region of the midbrain that surrounds the cerebral aqueduct; plays an essential role in various species-typical behaviors, including female sexual behavior.

parturition

The act of giving birth.

stria terminalis

A long fiber bundle that connects portions of the amygdala with the hypothalamus.

ventral tegmental area

A nucleus in the ventral midbrain; plays an essential role in maternal behavior.