Publications: R. Osuna

  • Shao, Y., L. S. Feldman-Cohen, and R. Osuna. 2008. Biochemical identification of base and phosphate contacts between Fis and a high-affinity DNA binding site. J. Mol. Biol. 380: 327-339.[abstract]
  • Shao, Y., L. S. Feldman-Cohen, and R. Osuna. 2008. Functional characterization of the Escherichia coli Fis-DNA binding sequence. J. Mol. Biol. 376:771-785. [abstract]
  • Bradley, M. D., M. B. Beach, A. P. Jason de Koning, T. S. Pratt, and R. Osuna. Effect of Fis on Escherichia coli gene expression during different growth stages. 2007. Microbiology 153:2922-2940. [abstract]
  • Mallik, P., B. J. Paul, S. T. Rutherford, R. L. Gourse, and R. Osuna. 2006. DksA is required for growth phase-dependent regulation, growth-rate control, and stringent control of fis expression in Escherichia coli. J. Bacteriol. 188:5775-5782. [abstract]
  • Meinhold, D., M. Beach, Y. Shao, R. Osuna, and W. Colón. 2006. The location of an engineered inter-subunit disulfide bond in FIS affects the denaturation pathway and cooperativity. Biochemistry 45:9767-9777. [abstract]
  • Feldman-Cohen, L. S., Y. Shao, D. Meinhold. C. Miller, W. Colón, and R. Osuna. 2006. Common and variable contributions of Fis residues to high-affinity binding at different DNA sequences. J. Bacteriol. 188:2081-2095. [abstract]
  • Walker, K. A., P. Mallik, T. S. Pratt, and R. Osuna. 2004. The Escherichia coli fis promoter is regulated by changes in the levels of its transcription initiation nucleotide CTP. J. Biol. Chem. 279:50818-50828. [abstract]
  • Mallik, P., T. S. Pratt, M. B. Beach, M. D. Bradley, J. Undamatla, and R. Osuna. 2004. Growth phase-dependent regulation and stringent control of fis are conserved processes in enteric bacteria and involve a single promoter ( fis P) in Escherichia coli . J. Bacteriol. 186:122- 135. [abstract]
  • Boswell, S., J. Matthew, M. Beach, R. Osuna, and W. Colón. 2004. Variable contributions of tyrosine residues to the structural and spectroscopic properties of the factor for inversion stimulation. Biochemistry 43:2964-2977. [abstract]
  • Walker, K.A., and R. Osuna. 2002. Factors affecting start site selection at the Escherichia coli fis promoter. J. Bacteriol. 184:4783-4791. [abstract]
  • Hobart, S.A., W. Meinfold, R. Osuna, and W. Colon. 2002. From two-state to three-state: effect of P61A mutation on the dynamics and stability of the factor for inversion stimulation results in na altered equilibrium denaturation mechanism. Biochemistry 41:13744-13754. [abstract]
  • Hobart, S.A., S. Ilin, D.F. Moriarty, R. Osuna, and W. Colon. 2002. Equilibrium denaturation studies of the Escherichia coli factor for inversion stimulation: implications for in vivo function. Protein Science 11:1671-1680. [abstract]
  • Walker, K.A., C.L. Atkins, and R. Osuna. 1999. Functional determinants of the Escherichia coli fis promoter: roles of -35, -10, and transcription initiation regions in the response to stringent control and growth phase-dependent regulation. J. Bacteriol. 181:1269-1280. [abstract]
  • Beach, M.B., and R. Osuna. 1998. Identification and characterization of the fis operon in enteric bacteria. J. Bacteriol. 180:5932-5946. [abstract]
  • Pratt, T.S., T. Steiner , L.S. Feldman, K.A. Walker, and R. Osuna. 1997.  Deletion analysis of the fis promoter region in Escherichia coli: antagonistic effects of integration host factor and Fis.  J. Bacteriol. 179:6367-6377 [abstract]
  • Osuna, R., D. Lineau, K. T. Hughes, and R. C. Johnson. 1995. Sequence, regulation, and functions of fis in Salmonella typhimurium. J. Bacteriol. 177: 2021-2032. [abstract]
  • Gosink, K. K., W. Ross, S. Leirmo, R. Osuna, S. E. Finkel, R. C. Johnson, and R. L. Gourse. 1993. DNA binding and bending are necessary but not sufficient for Fis-dependent activation of rrnB P1. J. Bacteriol. 175:1580-1589. [abstract]
  • Ball, C. A., R. Osuna, K. C. Ferguson, and R. C. Johnson. 1992. Dramatic changes in Fis levels upon nutrient upshift in Escherichia coli. J. Bacteriol. 174:8043-8056. [abstract]
  • Osuna, R., S. E. Finkel, and R. C. Johnson. 1991. Identification of two functional regions in Fis: the N-terminus is required to promote Hin-mediated DNA inversion but not lambda excision. EMBO J. 10:1593-1603. [abstract]
  • Osuna, R., B. K. Janes, and R. A. Bender. 1994. Roles of Catabolite Activator Protein sites centered at -81.5 and -41.5 in the activation of the Klebsiella aerogenes histidine utilization operon hutUH. J. Bacteriol. 176:5513-5524. [abstract]
  • Osuna, R., A. Schwacha, and R. A. Bender. 1994. Identification of the hutUH operator (hutUO) from Klebsiella aerogenes by DNA deletion analysis. J. Bacteriol. 176:5525-5529. [abstract]
  • Osuna, R. and R. A. Bender. 1991. Klebsiella aerogenes catabolite gene activator protein and the gene encoding it (crp). J. Bacteriol. 173:6626-663. [abstract]
  • Osuna, R., S. A. Boylan, and R. A. Bender. 1991. In vitro transcription of the histidine utilization (hutUH) operon from Klebsiella aerogenes. J. Bacteriol. 173:116-123. [abstract]
  • Morales, M.H., R. Osuna, and E. Sanchez. 1991. Vitellogenesis in Anolis pulchellus: induction of VTG-like protein in liver explants from male and immature lizards. J. Exp. Zool. 260:50-8. [abstract]