Dr. Millis began his research experience as a predoctoral trainee in molecular biology at the University of Pennsylvania and then extended that training into aspects gene regulation in human cells at the University of Washington School of Medicine. He was one of the first investigators to report roles for specific extracellular matrix molecules in processes related to cellular aging and disease. Subsequently he extended his scientific interests and technical repertoire into immunology and cancer biology at the Salk Institute in the laboratory of Professor Renato Dulbecco. His current research is a natural extension of these continuing interests into the roles of extracellular regulators in cell differentiation and human disease—and the utilization of evolving genomic information to address important health related problems. A consistent and continuing theme throughout is his belief in the importance of expert collaboration and synergy as a most effective and efficient means to progress to scientific understanding of biomedical processes and to facilitate the development of the new therapies and diagnostics that are required to help maintain a healthy population. His current research exemplifies that philosophy as it utilizes a synergistic approach to focus on the design and implementation of RNA based oligonucleotides [Aptamers] as intracellular delivery systems and extracellular targeting systems to diagnose or treat human disease conditions.
His research is currently funded by the National Cancer Institute-NIH.