Molecular Biology of Inteins

Inteins are remarkable for splicing at the
protein level!

We are excited to have recently discovered that inteins are adaptive elements that can regulate protein function. Because inteins exist in vital genes of microbial pathogens, they are targets of novel antibiotic development, another interest of our laboratory.

pathways

We study:

  • Rx BottleThe ability of inteins to regulate protein expression in response to environmental stress.

  • The structure, splicing properties and control of inteins.